Literature DB >> 6262530

Nucleotide sequence changes in polyoma virus A gene mutants.

T Thomas, P Vollmer, W R Folk.   

Abstract

The mutational alterations in polyoma virus mutants ts-a and ts-25E which cause their large T-antigens to be thermolabile have been identified. In ts-a, a G leads to A transition at nucleotide 2193 causes the replacement of Ala (GCT) by Thr (ACT). In ts-25E, a G leads to T transversion at nucleotide 2883 causes the replacement of Gly (GGC) by Cys (TGC). Revertants of both mutants have been isolated and shown to have the original nucleotides restored at these positions.

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Year:  1981        PMID: 6262530      PMCID: PMC171111     

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  34 in total

1.  ISOLATION OF TEMPERATURE-SENSITIVE MUTANTS OF POLYOMA VIRUS.

Authors:  M FRIED
Journal:  Virology       Date:  1965-04       Impact factor: 3.616

2.  The genome of human papovavirus BKV.

Authors:  I Seif; G Khoury; R Dhar
Journal:  Cell       Date:  1979-12       Impact factor: 41.582

3.  The genome of simian virus 40.

Authors:  V B Reddy; B Thimmappaya; R Dhar; K N Subramanian; B S Zain; J Pan; P K Ghosh; M L Celma; S M Weissman
Journal:  Science       Date:  1978-05-05       Impact factor: 47.728

4.  Complete nucleotide sequence of SV40 DNA.

Authors:  W Fiers; R Contreras; G Haegemann; R Rogiers; A Van de Voorde; H Van Heuverswyn; J Van Herreweghe; G Volckaert; M Ysebaert
Journal:  Nature       Date:  1978-05-11       Impact factor: 49.962

5.  Characterization of T antigens in polyoma-infected and transformed cells.

Authors:  M A Hutchinson; T Hunter; W Eckhart
Journal:  Cell       Date:  1978-09       Impact factor: 41.582

6.  Identification of the altered bases in mutated single-stranded DNA. IV. Nitrous acid induction of the transitions guanine to adenine and thymine to cytosine.

Authors:  A S Vanderbilt; I Tessman
Journal:  Genetics       Date:  1970-09       Impact factor: 4.562

7.  The nucleotide sequence and restriction enzyme sites of the polyoma genome.

Authors:  P L Deninger; A Esty; P LaPorte; H Hsu; T Friedmann
Journal:  Nucleic Acids Res       Date:  1980-02-25       Impact factor: 16.971

8.  Coding potential and regulatory signals of the polyoma virus genome.

Authors:  E Soeda; J R Arrand; N Smolar; J E Walsh; B E Griffin
Journal:  Nature       Date:  1980-01-31       Impact factor: 49.962

9.  Simian virus 40 mutants with deletions at the 3' end of the early region are defective in adenovirus helper function.

Authors:  C N Cole; L V Crawford; P Berg
Journal:  J Virol       Date:  1979-06       Impact factor: 5.103

10.  Characterization of polyoma virus T antigen.

Authors:  Y Ito; N Spurr; R Dulbecco
Journal:  Proc Natl Acad Sci U S A       Date:  1977-03       Impact factor: 11.205

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  12 in total

1.  Small and middle T antigens contribute to lytic and abortive polyomavirus infection.

Authors:  H Türler; C Salomon
Journal:  J Virol       Date:  1985-02       Impact factor: 5.103

2.  Activities of polyomavirus large-T-antigen proteins expressed by mutant genes.

Authors:  S V Nilsson; G Magnusson
Journal:  J Virol       Date:  1984-09       Impact factor: 5.103

3.  RNA footprint mapping of RNA polymerase II molecules stalled in the intergenic region of polyomavirus DNA.

Authors:  F Brabant; N H Acheson
Journal:  J Virol       Date:  1995-07       Impact factor: 5.103

4.  Regulation of polyomavirus transcription by large tumor antigen.

Authors:  W G Farmerie; W R Folk
Journal:  Proc Natl Acad Sci U S A       Date:  1984-11       Impact factor: 11.205

5.  Nucleotide sequence changes in polyoma ts-a mutants: correlation with protein structure.

Authors:  P L Deininger; P LaPorte; T Friedmann
Journal:  J Virol       Date:  1981-03       Impact factor: 5.103

6.  Loss of polyoma virus infectivity as a result of a single amino acid change in a region of polyoma virus large T-antigen which has extensive amino acid homology with simian virus 40 large T-antigen.

Authors:  A C Hayday; F Chaudry; M Fried
Journal:  J Virol       Date:  1983-02       Impact factor: 5.103

7.  Expression of the large T protein of polyoma virus promotes the establishment in culture of "normal" rodent fibroblast cell lines.

Authors:  M Rassoulzadegan; Z Naghashfar; A Cowie; A Carr; M Grisoni; R Kamen; F Cuzin
Journal:  Proc Natl Acad Sci U S A       Date:  1983-07       Impact factor: 11.205

8.  Simian virus 40 and polyomavirus large tumor antigens have different requirements for high-affinity sequence-specific DNA binding.

Authors:  A Scheller; C Prives
Journal:  J Virol       Date:  1985-05       Impact factor: 5.103

9.  T-antigen-independent replication of polyomavirus DNA in murine embryonal carcinoma cells.

Authors:  L Dandolo; J Aghion; D Blangy
Journal:  Mol Cell Biol       Date:  1984-02       Impact factor: 4.272

10.  Polyoma mutants that productively infect F9 embryonal carcinoma cells do not rescue wild-type polyoma in F9 cells.

Authors:  F K Fujimura; E Linney
Journal:  Proc Natl Acad Sci U S A       Date:  1982-03       Impact factor: 11.205

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