Literature DB >> 6262260

Radioprotection of bovine erythrocytes to haemolysis.

G Bartosz, W Leyko.   

Abstract

The effect of several free-radical scavengers on the radiation-induced haemolysis of bovine erythrocytes (50 krad, 60Co, cell concentration: 0.05 v/v) was studied. A two-phase effect of the additives was found with a maximum of the protective action in the millimolar concentration range. A correlation was established between the degree of protection at a fixed concentration (5mM) and the rate constants of reactions of respective compounds with OH. A radiosensitizing effect of diethyldithiocarbamate, an inhibitor of superoxide dismutase (SOD) was not confirmed and no specific protective effect of SOD was seen.

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Year:  1981        PMID： 6262260     DOI： 10.1080/09553008114550051

Source DB:  PubMed          Journal:  Int J Radiat Biol Relat Stud Phys Chem Med        ISSN： 0020-7616


  3 in total

1.  Heavy ion induced membrane damage: hemolysis of erythrocytes and changes in erythrocyte membrane fluidity.

Authors:  W Schön; C Ziegler; H Gärtner; G Kraft
Journal:  Radiat Environ Biophys       Date:  1994       Impact factor: 1.925

2.  Ionizing radiation-induced structural modification of human red blood cells.

Authors:  K Gwoździński
Journal:  Radiat Environ Biophys       Date:  1991       Impact factor: 1.925

3.  Lipid peroxidation and haemoglobin degradation in red blood cells exposed to t-butyl hydroperoxide. The relative roles of haem- and glutathione-dependent decomposition of t-butyl hydroperoxide and membrane lipid hydroperoxides in lipid peroxidation and haemolysis.

Authors:  R J Trotta; S G Sullivan; A Stern
Journal:  Biochem J       Date:  1983-06-15       Impact factor: 3.857
  3 in total

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