Literature DB >> 6261411

Maternal inheritance of mitochondrial DNA polymorphisms in cultured human fibroblasts.

J T Case, D C Wallace.   

Abstract

We have isolated the total cellular DNA from the cultured diploid fibroblasts of a six-member, three-generation human family. Using a specific radioactive probe for mitochondrial (mt) sequences we have identified new polymorphic variants in this family for the Hhal restriction endonuclease cleavage pattern of the mtDNA. The inheritance of these cleavage patterns verifies the maternal inheritance of mtDNA through all three generations.

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Year:  1981        PMID： 6261411     DOI： 10.1007/bf01544751

Source DB:  PubMed          Journal:  Somatic Cell Genet        ISSN： 0098-0366


  19 in total

1.  The frequency of heteroplasmy in the HVII region of mtDNA differs across tissue types and increases with age.

Authors:  C D Calloway; R L Reynolds; G L Herrin; W W Anderson
Journal:  Am J Hum Genet       Date:  2000-03-17       Impact factor: 11.025

Review 2.  Freezer anthropology: new uses for old blood.

Authors:  D A Merriwether
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1999-01-29       Impact factor: 6.237

3.  Southeast Asian mitochondrial DNA analysis reveals genetic continuity of ancient mongoloid migrations.

Authors:  S W Ballinger; T G Schurr; A Torroni; Y Y Gan; J A Hodge; K Hassan; K H Chen; D C Wallace
Journal:  Genetics       Date:  1992-01       Impact factor: 4.562

4.  Mitochondrial genetics: principles and practice.

Authors:  J M Shoffner; D C Wallace
Journal:  Am J Hum Genet       Date:  1992-12       Impact factor: 11.025

5.  1994 William Allan Award Address. Mitochondrial DNA variation in human evolution, degenerative disease, and aging.

Authors:  D C Wallace
Journal:  Am J Hum Genet       Date:  1995-08       Impact factor: 11.025

6.  Ethnic variation in Hpa 1 endonuclease cleavage patterns of human mitochondrial DNA.

Authors:  M Denaro; H Blanc; M J Johnson; K H Chen; E Wilmsen; L L Cavalli-Sforza; D C Wallace
Journal:  Proc Natl Acad Sci U S A       Date:  1981-09       Impact factor: 11.205

7.  Complete moles have paternal chromosomes but maternal mitochondrial DNA.

Authors:  D C Wallace; U Surti; C W Adams; A E Szulman
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132

8.  Length mutations in human mitochondrial DNA.

Authors:  R L Cann; A C Wilson
Journal:  Genetics       Date:  1983-08       Impact factor: 4.562

9.  Segregation of mitochondrial DNA in human somatic cell hybrids.

Authors:  F A White; C L Bunn
Journal:  Mol Gen Genet       Date:  1984

10.  A new disease-related mutation for mitochondrial encephalopathy lactic acidosis and strokelike episodes (MELAS) syndrome affects the ND4 subunit of the respiratory complex I.

Authors:  P Lertrit; A S Noer; M J Jean-Francois; R Kapsa; X Dennett; D Thyagarajan; K Lethlean; E Byrne; S Marzuki
Journal:  Am J Hum Genet       Date:  1992-09       Impact factor: 11.025
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