Literature DB >> 6258761

Differential diagnosis of hypoparathyroid disorders during childhood.

M Ishida, Y Seino, T Simotsuji, T Ishii, K Yamaoka, T Harada, H yabuuchi, K Nishimura.   

Abstract

Changes in the plasma and urinary adenosine 3', 5' monophosphate (cyclic AMP) levels on infusion of parathyroid hormone were studied in 10 normal children, 5 children with idiopathic hypoparathyroidism, and 3 children with pseudohypoparathyroidism. In normal children the plasma concentration of cyclic AMP ranges from 18.0 to 68.0 pmoles/ml under basal conditions, and increases to a peak of about 10-fold the basal level 5 min after infusion of parathyroid hormone. Infusion of parathyroid hormone caused no increase in plasma cyclic AMP in patients with pseudohypoparathyroidism but about 18-fold increase in those with idiopathic hypoparathyroidism. The measurement of plasma cyclic AMP before and 5 min after infusion of parathyroid hormone is concluded to be a single and effective method for differential diagnosis of hypoparathyroid disorders.

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Year:  1980        PMID: 6258761     DOI: 10.1007/bf02407182

Source DB:  PubMed          Journal:  Calcif Tissue Int        ISSN: 0171-967X            Impact factor:   4.333


  12 in total

1.  Circadian variations in plasma 3':5'-cyclic adenosine monophosphate and 3':5'-cyclic guanosine monophosphate of normal adults.

Authors:  M Mikuni; Y Saito; T Koyama; M Daiguji; I Yamashita; K Yamazaki; M Honma; M Ui
Journal:  Life Sci       Date:  1978-02       Impact factor: 5.037

2.  An ultrasensitive method for the simultaneous determination of cyclic AMP and cyclic GMP in small-volume samples from blood and tissue.

Authors:  M Honma; T Satoh; J Takezawa; M Ui
Journal:  Biochem Med       Date:  1977-12

3.  1,25-Dihydroxyvitamin D3: mode of action in intestine and parathyroid glands, assay in humans and isolation of its glycoside from Solanum malacoxylon.

Authors:  M R Haussler; M R Hughes; T A McCain; J E Zerwekh; P F Brumbaugh; W Jubiz; R H Wasserman
Journal:  Calcif Tissue Res       Date:  1977-05

4.  The effects of exogenous parathyroid hormone on plasma and urinary adenosine 3', 5'-cyclic monophosphate in man.

Authors:  S Tomlinson; P M Barling; J D Albano; B L Brown; J L O'Riordan
Journal:  Clin Sci Mol Med       Date:  1974-11

5.  Parathyroid function and the renal excretion of 3'5'-adenylic acid.

Authors:  L R Chase; G D Aurbach
Journal:  Proc Natl Acad Sci U S A       Date:  1967-08       Impact factor: 11.205

6.  A simplified assessment of response to parathyroid hormone in hypoparathyroid patients.

Authors:  S Tomlinson; G N Hendy; J H O'Riordan
Journal:  Lancet       Date:  1976-01-10       Impact factor: 79.321

7.  Competitive protein binding assay for 1,25-dihydroxy-vitamin D in human plasma.

Authors:  S Dokoh; R Morita; M Fukunaga; I Yamamoto; K Torizuka
Journal:  Endocrinol Jpn       Date:  1978-10

8.  Pseudohypoparathyroidism: defective excretion of 3',5'-AMP in response to parathyroid hormone.

Authors:  L R Chase; G L Melson; G D Aurbach
Journal:  J Clin Invest       Date:  1969-10       Impact factor: 14.808

9.  Effects of parathyroid hormone on plasma and urinary adenosine 3',5'-monophosphate in man.

Authors:  N I Kaminsky; A E Broadus; J G Hardman; D J Jones; J H Ball; E W Sutherland; G W Liddle
Journal:  J Clin Invest       Date:  1970-12       Impact factor: 14.808

10.  Plasma 1,25-dihydroxyvitamin D concentrations in cords, newborns, infants, and children.

Authors:  Y Seino; T Shimotsuji; K Yamaoka; M Ishida; T Ishii; S Matsuda; C Ikehara; H Yabuuchi; S Dokoh
Journal:  Calcif Tissue Int       Date:  1980       Impact factor: 4.333

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