Literature DB >> 6258744

Is aspartic acid the neurotransmitter of the perforant pathway?

A Di Lauro, R W Schmid, J L Meek.   

Abstract

In order to determine whether an amino acid may act as a neurotransmitter in the perforant pathway we examined the effect of lesion of rat entorhinal cortex on the concentrations of various amino acids in the hippocampus proper and fascia dentata. Only the aspartic acid content was found significantly decreased after the lesion. This decreases is not due to a loss from target cells of the perforant pathway, but rather to a loss from its degenerating terminals.

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Year:  1981        PMID: 6258744     DOI: 10.1016/0006-8993(81)90382-6

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  3 in total

1.  Neurochemical characteristics of neurons of the human hippocampal formation.

Authors:  I V Dyuizen; V E Okhotin; S G Kalinichenko; P A Motavkin
Journal:  Neurosci Behav Physiol       Date:  1998 Jan-Feb

2.  The localization of leucine-enkephalin immunoreactivity within the guinea pig hippocampus.

Authors:  A M Tielen; F W van Leeuwen; F H Lopes da Silva
Journal:  Exp Brain Res       Date:  1982       Impact factor: 1.972

3.  Correlation between long-term potentiation and release of endogenous amino acids from dentate gyrus of anaesthetized rats.

Authors:  T V Bliss; R M Douglas; M L Errington; M A Lynch
Journal:  J Physiol       Date:  1986-08       Impact factor: 5.182

  3 in total

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