Literature DB >> 6258020

The tetracycline-resistance transposon Tn10 inhibits translocation of Tn10.

C F Beck, H Moyed, J L Ingraham.   

Abstract

Using a set of overlapping deletion mutants in the tetracycline-resistance transposon Tn10, it has been established that certain regions of the Tn10 genome exert a powerful inhibition on translocation of an intact Tn10 element into the bacterial genome. Such inhibition is strongly temperature dependent: at 37 degrees C translocation is inhibited by at least a factor of 100; no inhibition of translocation is detected at 30 degrees C.

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Year:  1980        PMID: 6258020     DOI: 10.1007/bf00425476

Source DB:  PubMed          Journal:  Mol Gen Genet        ISSN: 0026-8925


  13 in total

1.  Mutagenesis by insertion of a drug-resistance element carrying an inverted repetition.

Authors:  N Kleckner; R K Chan; B K Tye; D Botstein
Journal:  J Mol Biol       Date:  1975-10-05       Impact factor: 5.469

2.  Acetylornithinase of Escherichia coli: partial purification and some properties.

Authors:  H J VOGEL; D M BONNER
Journal:  J Biol Chem       Date:  1956-01       Impact factor: 5.157

3.  In vitro mutagenesis of a circular DNA molecule by using synthetic restriction sites.

Authors:  F Heffron; M So; B J McCarthy
Journal:  Proc Natl Acad Sci U S A       Date:  1978-12       Impact factor: 11.205

4.  Effect of temperature on translocation frequency of the Tn3 element.

Authors:  P J Kretschmer; S N Cohen
Journal:  J Bacteriol       Date:  1979-08       Impact factor: 3.490

5.  Genetic engineering in vivo using translocatable drug-resistance elements. New methods in bacterial genetics.

Authors:  N Kleckner; J Roth; D Botstein
Journal:  J Mol Biol       Date:  1977-10-15       Impact factor: 5.469

6.  Lac repressor can be fused to beta-galactosidase.

Authors:  B Müller-Hill; J Kania
Journal:  Nature       Date:  1974-06-07       Impact factor: 49.962

7.  Inhibition of TnA translocation by TnA.

Authors:  M K Robinson; P M Bennett; M H Richmond
Journal:  J Bacteriol       Date:  1977-01       Impact factor: 3.490

8.  A genetic approach to analysis of transposons.

Authors:  C F Beck
Journal:  Proc Natl Acad Sci U S A       Date:  1979-05       Impact factor: 11.205

9.  Deletions affecting the transposition of an antibiotic resistance gene.

Authors:  F Heffron; P Bedinger; J J Champoux; S Falkow
Journal:  Proc Natl Acad Sci U S A       Date:  1977-02       Impact factor: 11.205

10.  Resistance of Escherichia coli to tetracyclines. Changes in permeability to tetracyclines in Escherichia coli bearing transferable resistance factors.

Authors:  T J Franklin
Journal:  Biochem J       Date:  1967-10       Impact factor: 3.857

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  2 in total

1.  The requirement for both DNA polymerase and 5' to 3' exonuclease activities of DNA polymerase I during Tn5 transposition.

Authors:  C Sasakawa; Y Uno; M Yoshikawa
Journal:  Mol Gen Genet       Date:  1981

2.  Insertion element IS5 contains a third gene.

Authors:  B Rak; M von Reutern
Journal:  EMBO J       Date:  1984-04       Impact factor: 11.598

  2 in total

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