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Literature DB >> 6257930

Structure of and alterations to defective murine sarcoma virus particles lacking envelope proteins and core polyprotein cleavage.

Abstract

HTG2 hamster cells produce a defective murine sarcoma virus lacking gp70 and, consequently, viral surface projections (knobs), but the lack of knobs appears to have no effect on intramembrane particle distribution. In addition, it has been noted that the core of the virus remains in the "immature" form as a result of the failure of the polyprotein precursor (p65) to undergo cleavage. However, incubation of HTG2 virus with avian myoblastosis virus was found to yield specific cleavage products of p65.

Entities: Disease Gene Species

Mesh：

Substances：
Viral Proteins

Year: 1980 PMID： 6257930 PMCID： PMC353714

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

20 in total

1. Absence of surface projections of some noninfectious forms of RSV.

Authors: C de Giuli; S Kawai; S Dales; H Hanafusa
Journal: Virology Date: 1975-07 Impact factor: 3.616

2. Application of freeze-drying intact cells to studies of murine oncornavirus morphogenesis.

Authors: A Demsey; D Kawka; C W Stackpole
Journal: J Virol Date: 1977-01 Impact factor: 5.103

3. Assembly of type C oncornaviruses: a model.

Authors: D P Bolognesi; R C Montelaro; H Frank; W Schäfer
Journal: Science Date: 1978-01-13 Impact factor: 47.728

4. Synthesis and processing of precursor polypeptides to murine mammary tumor virus structural proteins.

Authors: J Racevskis; N H Sarkar
Journal: J Virol Date: 1978-01 Impact factor: 5.103

5. Characterization of Rauscher Leukemia virus (RLV) P40-42, an intermediate cleavage product of the group specific antigen (gag) precursor polypeptide, P65-70.

Authors: Y Yoshinaka; R B Luftig
Journal: Biochem Biophys Res Commun Date: 1977-11-07 Impact factor: 3.575

6. Partial characterization of a P70 proteolytic factor that is present in purified virions of Rauscher leukemia virus (RLV).

Authors: Y Yoshinaka; R B Luftig
Journal: Biochem Biophys Res Commun Date: 1977-05-09 Impact factor: 3.575

Structure of and alterations to defective murine sarcoma virus particles lacking envelope proteins and core polyprotein cleavage.

1. Absence of surface projections of some noninfectious forms of RSV.

2. Application of freeze-drying intact cells to studies of murine oncornavirus morphogenesis.

3. Assembly of type C oncornaviruses: a model.

4. Synthesis and processing of precursor polypeptides to murine mammary tumor virus structural proteins.

5. Characterization of Rauscher Leukemia virus (RLV) P40-42, an intermediate cleavage product of the group specific antigen (gag) precursor polypeptide, P65-70.

6. Partial characterization of a P70 proteolytic factor that is present in purified virions of Rauscher leukemia virus (RLV).

Review 7. Viral envelopes and their relationship to cellular membranes.

8. Membrane alterations which accompany MuMTV maturation. I. Studies by freeze-cleave techniques.

Review 9. Theoretical aspects of structure and assembly of viral envelops.

10. Properties of a P70 proteolytic factor of murine leukemia viruses.

1. Synthetic peptides as substrates and inhibitors of a retroviral protease.

2. Proteolytic processing of Ty3 proteins is required for transposition.