| Literature DB >> 6257836 |
Abstract
We report for the first time the replication of infectious adeno-associated virus type 1 (AAV-1) in rodent cells [primary mouse kidney (PMK) and mouse L929 cells] using murine adenovirus (MAV) as a helper virus and also the production of AAV-I virus antigen by herpes simplex virus type I (HSV-I) with its temperature-sensitive mutant ts 200 in mouse neuroblastoma (NB) cells. The infectious AAV virions produced by MAV on L cells had a buoyant density of 1.41 2ml in caesium chloride gradients.Entities:
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Year: 1980 PMID： 6257836 DOI： 10.1099/0022-1317-51-1-223
Source DB: PubMed Journal: J Gen Virol ISSN： 0022-1317 Impact factor: 3.891