Literature DB >> 6256656

A position effect in the control of transcription at yeast mating type loci.

K A Nasmyth, K Tatchell, B D Hall, C Astell, M Smith.   

Abstract

The two mating type loci MATa and MAT alpha each produce two mRNAs that are transcribed in opposite and diverging directions from central promoters. Silent copies of MATa (HMRa) and MAT alpha (HML alpha) contain identical DNA sequences throughout the transcribed region, yet are not transcribed. It is concluded that sequences to the left of HMRa (and probably HML alpha) must somehow affect transcription initiated at the centre of each locus 700 to 1,400 base pairs away. A possible mechanism for this position effect is discussed.

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Year:  1981        PMID： 6256656     DOI： 10.1038/289244a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  92 in total

1.  Cloning and comparison of A alpha mating-type alleles of the Basidiomycete Schizophyllum commune.

Authors:  L Giasson; C A Specht; C Milgrim; C P Novotny; R C Ullrich
Journal:  Mol Gen Genet       Date:  1989-07

2.  Disruption of a silencer domain by a retrotransposon.

Authors:  M F Mastrangelo; K G Weinstock; B K Shafer; A M Hedge; D J Garfinkel; J N Strathern
Journal:  Genetics       Date:  1992-07       Impact factor: 4.562

3.  A cis-acting tRNA gene imposes the cell cycle progression requirement for establishing silencing at the HMR locus in yeast.

Authors:  Asmitha G Lazarus; Scott G Holmes
Journal:  Genetics       Date:  2010-12-06       Impact factor: 4.562

4.  Differential repair of UV damage in Saccharomyces cerevisiae.

Authors:  C Terleth; C A van Sluis; P van de Putte
Journal:  Nucleic Acids Res       Date:  1989-06-26       Impact factor: 16.971

5.  The MF alpha 1 gene of Saccharomyces cerevisiae: genetic mapping and mutational analysis of promoter elements.

Authors:  M C Flessel; A J Brake; J Thorner
Journal:  Genetics       Date:  1989-02       Impact factor: 4.562

6.  Regulation by the yeast mating-type locus of STE12, a gene required for cell-type-specific expression.

Authors:  S Fields; I Herskowitz
Journal:  Mol Cell Biol       Date:  1987-10       Impact factor: 4.272

7.  New alleles of SIR2 define cell-cycle-specific silencing functions.

Authors:  Mirela Matecic; Kristen Martins-Taylor; Merrit Hickman; Jason Tanny; Danesh Moazed; Scott G Holmes
Journal:  Genetics       Date:  2006-06-18       Impact factor: 4.562

8.  Negative control for the initiation of meiosis in Schizosaccharomyces pombe.

Authors:  Y Iino; M Yamamoto
Journal:  Proc Natl Acad Sci U S A       Date:  1985-04       Impact factor: 11.205

9.  The homeobox gene ATK1 of Arabidopsis thaliana is expressed in the shoot apex of the seedling and in flowers and inflorescence stems of mature plants.

Authors:  J Dockx; N Quaedvlieg; G Keultjes; P Kock; P Weisbeek; S Smeekens
Journal:  Plant Mol Biol       Date:  1995-07       Impact factor: 4.076

10.  The telotype defines the telomere state in Saccharomyces cerevisiae and is inherited as a dominant non-Mendelian characteristic in cells lacking telomerase.

Authors:  Svetlana Makovets; Tanya L Williams; Elizabeth H Blackburn
Journal:  Genetics       Date:  2008-01       Impact factor: 4.562
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