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Literature DB >> 6256361

HeLa ribosomal protein S6. Insulin and dibutyryl cyclic AMP affect different phosphopeptides.

Abstract

Tryptic phosphopeptides from HeLa ribosomal protein S6 have been separated by chromatography, followed by electrophoresis. Three phosphopeptides were found in S6 from cells treated in vivo with dibutyryl cAMP and at least four different phosphopeptides were found from cells treated with insulin plus the essential amino acids. Only phosphoserine was found in S6 isolated from insulin-treated cells.

Entities: Chemical Gene

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Year: 1981 PMID： 6256361

Source DB: PubMed Journal: J Biol Chem ISSN： 0021-9258 Impact factor: 5.157

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Cited

15 in total

1. Evidence that a 90-kDa phosphoprotein, an associated kinase, and a specific phosphatase are involved in the regulation of Cloudman melanoma cell proliferation by insulin.

Authors: R D Fleischmann; J M Pawelek
Journal: Proc Natl Acad Sci U S A Date: 1985-02 Impact factor: 11.205

2. Evidence that insulin activates fat-cell acetyl-CoA carboxylase by increased phosphorylation at a specific site.

Authors: R W Brownsey; R M Denton
Journal: Biochem J Date: 1982-01-15 Impact factor: 3.857

Review 3. A partial view of the mechanism of insulin action.

Authors: R M Denton; R W Brownsey; G J Belsham
Journal: Diabetologia Date: 1981-10 Impact factor: 10.122

4. Influence of the state of ribosome association on the phosphorylation of ribosomal proteins in isolated ribosome--protein kinase systems from rat cerebral cortex.

Authors: T A Francis; S Roberts
Journal: Biochem J Date: 1982-11-15 Impact factor: 3.857

5. Inhibition of cerebral protein kinase activity and cyclic AMP-dependent ribosomal-protein phosphorylation in experimental hyperphenylalaninaemia.

Authors: S Roberts; B S Morelos
Journal: Biochem J Date: 1982-02-15 Impact factor: 3.857

HeLa ribosomal protein S6. Insulin and dibutyryl cyclic AMP affect different phosphopeptides.

1. Evidence that a 90-kDa phosphoprotein, an associated kinase, and a specific phosphatase are involved in the regulation of Cloudman melanoma cell proliferation by insulin.

2. Evidence that insulin activates fat-cell acetyl-CoA carboxylase by increased phosphorylation at a specific site.

Review 3. A partial view of the mechanism of insulin action.

4. Influence of the state of ribosome association on the phosphorylation of ribosomal proteins in isolated ribosome--protein kinase systems from rat cerebral cortex.

5. Inhibition of cerebral protein kinase activity and cyclic AMP-dependent ribosomal-protein phosphorylation in experimental hyperphenylalaninaemia.

6. Impaired tracheobronchial clearance in patients with mild stable asthma.

7. Activation of S6 kinase activity in 3T3-L1 cells by insulin and phorbol ester.

8. Increased phosphorylation of ribosomal protein S6 during meiotic maturation of Xenopus oocytes.

9. Identification of multifunctional ATP-citrate lyase kinase as the alpha-isoform of glycogen synthase kinase-3.

10. Purified rat brain calcium- and phospholipid-dependent protein kinase phosphorylates ribosomal protein S6.