Literature DB >> 6256180

alpha 2-Adrenergic receptors are associated with renal proximal tubules.

W S Young, M J Kuhar.   

Abstract

The location of alpha 2-adrenergic receptors has been investigated in the guinea pig kidney. We used an in vitro labeling autoradiographic technique to examine the distribution of specific [3H]clonidine binding sites with the light microscope. alpha 2-Adrenergic receptors appeared to be located predominantly on the proximal tubules. The implication of this finding for renal physiology is discussed.

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Year:  1980        PMID： 6256180     DOI： 10.1016/0014-2999(80)90194-6

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  3 in total

1.  [3H]-rauwolscine binding to alpha 2-adrenoceptors in the mammalian kidney: apparent receptor heterogeneity between species.

Authors:  C B Neylon; R J Summers
Journal:  Br J Pharmacol       Date:  1985-06       Impact factor: 8.739

2.  Functional characterization of the alpha adrenergic receptor modulating the hydroosmotic effect of vasopressin on the rabbit cortical collecting tubule.

Authors:  R K Krothapalli; W N Suki
Journal:  J Clin Invest       Date:  1984-03       Impact factor: 14.808

3.  Alpha 2 adrenergic agonists stimulate Na+-H+ antiport activity in the rabbit renal proximal tubule.

Authors:  E P Nord; M J Howard; A Hafezi; P Moradeshagi; S Vaystub; P A Insel
Journal:  J Clin Invest       Date:  1987-12       Impact factor: 14.808
  3 in total

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