Literature DB >> 6255563

Binding and mobility of the cell surface receptors for 3,3',5-triiodo-L-thyronine.

F R Maxfield, M C Willingham, I Pastan, P Dragsten, S Y Cheng.   

Abstract

A fluorescent derivative of the thyroid hormone 3,3'-triiodo-L-thyronine binds to cultured mouse fibroblasts; such binding is saturable. Video intensification fluorescence microscopy indicates that binding occurs at the plasma membrane. Diffusion coefficients, obtained by fluorescence photobleaching recovery, are consistent with binding to a protein receptor on the cell surface.

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Year:  1981        PMID： 6255563     DOI： 10.1126/science.6255563

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  7 in total

Review 1.  Multiple mechanisms for regulation of the transcriptional activity of thyroid hormone receptors.

Authors:  S Y Cheng
Journal:  Rev Endocr Metab Disord       Date:  2000-01       Impact factor: 6.514

2.  Morphologic study of the internalization of a lysosomal enzyme by the mannose 6-phosphate receptor in cultured Chinese hamster ovary cells.

Authors:  M C Willingham; I H Pastan; G G Sahagian; G W Jourdian; E F Neufeld
Journal:  Proc Natl Acad Sci U S A       Date:  1981-11       Impact factor: 11.205

3.  Plasma membrane transport of thyroid hormone: its possible pathophysiological significance.

Authors:  E P Krenning; R Docter; T J Visser; G Hennemann
Journal:  J Endocrinol Invest       Date:  1983-02       Impact factor: 4.256

4.  Ultrastructural distribution of interferon receptor sites on mouse L fibroblasts grown in suspension: ganglioside blockade of ligand binding.

Authors:  V M Kushnaryov; H S MacDonald; J J Sedmak; S E Grossberg
Journal:  Infect Immun       Date:  1983-04       Impact factor: 3.441

5.  Affinity labeling of the plasma membrane 3,3',5-triiodo-L-thyronine receptor in GH3 cells.

Authors:  R Horiuchi; M L Johnson; M C Willingham; I Pastan; S Cheng
Journal:  Proc Natl Acad Sci U S A       Date:  1982-09       Impact factor: 11.205

6.  Specific binding sites for the triiodothyronine in the plasma membrane of rat thymocytes. Correlation with biochemical responses.

Authors:  J Segal; S H Ingbar
Journal:  J Clin Invest       Date:  1982-11       Impact factor: 14.808

7.  Mitochondrial binding of triiodothyronine (T3). Demonstration by electron-microscopic radioautography of dispersed liver cells.

Authors:  K Sterling; G A Campbell; G S Taliadouros; E A Nunez
Journal:  Cell Tissue Res       Date:  1984       Impact factor: 5.249
  7 in total

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