| Literature DB >> 6254894 |
A J Rao, C Behrens, J Ramachandran.
Abstract
A radioimmunoassay using specifically tritiated corticotropin (3H-ACTH) of high specific radioactivity (46 Ci/mmol) and full biological activity has been developed. The assay is sensitive to ACTH in the range 200 pg-10 ng. 50% displacement of 3H-ACTH is produced by less than a twofold excess of unlabeled hormone. Immunochemical studies with various ACTH analogs showed that the antiserum recognized the intact molecule better than any of other fragments.Entities:
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Year: 1980 PMID： 6254894 DOI： 10.1111/j.1399-3011.1980.tb02925.x
Source DB: PubMed Journal: Int J Pept Protein Res ISSN： 0367-8377