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Literature DB >> 6254158

Modulation of epidermal growth factor receptors on 3T3 cells by platelet-derived growth factor.

Abstract

Platelet-derived growth factor does not compete with epidermal growth factor (EGF) for binding to EGF receptors on the murine 3T3 cell surface, but it modulates EGF receptors in two ways: (i) it induces a transient down regulation of EGF receptors and (ii) it inhibits EGF-induced down regulation of EGF receptors. These data suggest a common cellular internalization mechanism for the receptors for both hormones.

Entities: Gene Species

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Year: 1980 PMID： 6254158 DOI： 10.1126/science.6254158

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

28 in total

1. Modulation of epidermal growth factor receptors by human alpha interferon.

Authors: K C Zoon; Y Karasaki; D L zur Nedden; R Q Hu; H Arnheiter
Journal: Proc Natl Acad Sci U S A Date: 1986-11 Impact factor: 11.205

2. Platelet-derived growth factor stimulates phagocytosis and blocks agonist-induced activation of the neutrophil oxidative burst: a possible cellular mechanism to protect against oxygen radical damage.

Authors: E Wilson; S M Laster; L R Gooding; J D Lambeth
Journal: Proc Natl Acad Sci U S A Date: 1987-04 Impact factor: 11.205

3. Kinetics and regulation of the tyrosine phosphorylation of epidermal growth factor receptor in intact A431 cells.

Authors: E Sturani; R Zippel; L Toschi; L Morello; P M Comoglio; L Alberghina
Journal: Mol Cell Biol Date: 1988-03 Impact factor: 4.272

4. Platelet-derived growth factor mimics phorbol diester action on epidermal growth factor receptor phosphorylation at threonine-654.

Authors: R J Davis; M P Czech
Journal: Proc Natl Acad Sci U S A Date: 1985-06 Impact factor: 11.205

5. Effects of vinorelbine on epidermal growth factor-receptor binding of human breast cancer cell lines in vitro.

Authors: H Depenbrock; A Shirvani; J Rastetter; A R Hanauske
Journal: Invest New Drugs Date: 1995 Impact factor: 3.850

6. Epidermal growth factor (EGF) modulation of feline sarcoma virus fms tyrosine kinase activity, internalization, degradation, and transforming potential in an EGF receptor/v-fms chimera.

Authors: H Riedel
Journal: J Virol Date: 1994-01 Impact factor: 5.103

Modulation of epidermal growth factor receptors on 3T3 cells by platelet-derived growth factor.

1. Modulation of epidermal growth factor receptors by human alpha interferon.

2. Platelet-derived growth factor stimulates phagocytosis and blocks agonist-induced activation of the neutrophil oxidative burst: a possible cellular mechanism to protect against oxygen radical damage.

3. Kinetics and regulation of the tyrosine phosphorylation of epidermal growth factor receptor in intact A431 cells.

4. Platelet-derived growth factor mimics phorbol diester action on epidermal growth factor receptor phosphorylation at threonine-654.

5. Effects of vinorelbine on epidermal growth factor-receptor binding of human breast cancer cell lines in vitro.

6. Epidermal growth factor (EGF) modulation of feline sarcoma virus fms tyrosine kinase activity, internalization, degradation, and transforming potential in an EGF receptor/v-fms chimera.

7. Platelet-derived growth factor-modulated proteins: constitutive synthesis by a transformed cell line.

8. The distribution of PDGFs and PDGF-receptors during murine secondary palate development.

9. Sharing of biological effect and receptors between guinea pig insulin and platelet-derived growth factor.

10. Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit.