Literature DB >> 6254154

Vasoactive intestinal peptide: a possible transmitter of nonadrenergic relaxation of guinea pig airways.

Y Matsuzaki, Y Hamasaki, S I Said.   

Abstract

Vasoactive intestinal peptide, a smooth-muscle relaxant neuropeptide with neurotransmitter properties, was relaxed during electrical field stimulation of guinea pig trachea. The amount released correlated with the degree of relaxation, and the release was blocked by tetrodotoxin. Prior incubation of the trachea with antiserum to vasoactive intestinal peptide reduced the relaxation. Thus vasoactive intestinal peptide may mediate the nonadrenergic relaxation of tracheal smooth muscle.

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Year:  1980        PMID： 6254154     DOI： 10.1126/science.6254154

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  41 in total

1.  Non-adrenergic, non-cholinergic neural activation stabilizes smooth-muscle tone independently of eicosanoid factors in guinea-pig isolated airways.

Authors:  A Lindén; A Ullman; C G Löfdahl; B E Skoogh
Journal:  Br J Pharmacol       Date:  1991-10       Impact factor: 8.739

2.  Effects of epithelium removal on relaxation of airway smooth muscle induced by vasoactive intestinal peptide and electrical field stimulation.

Authors:  S G Farmer; J Togo
Journal:  Br J Pharmacol       Date:  1990-05       Impact factor: 8.739

3.  Effects of vasoactive intestinal polypeptide on antigen-induced bronchoconstriction and thromboxane release in guinea-pig lung.

Authors:  G Ciabattoni; P Montuschi; D Currò; G Togna; P Preziosi
Journal:  Br J Pharmacol       Date:  1993-05       Impact factor: 8.739

4.  Relaxant innervation of the guinea-pig trachealis: demonstration of capsaicin-sensitive and -insensitive vagal pathways.

Authors:  B J Canning; B J Undem
Journal:  J Physiol       Date:  1993-01       Impact factor: 5.182

5.  Occurrence and distribution of GRP-immunoreactive nerve fibres in the respiratory tract.

Authors:  R Uddman; E Moghimzadeh; F Sundler
Journal:  Arch Otorhinolaryngol       Date:  1984

6.  Effect of infused vasoactive intestinal peptide on airway function in normal subjects.

Authors:  J B Palmer; F M Cuss; J B Warren; M Blank; S R Bloom; P J Barnes
Journal:  Thorax       Date:  1986-09       Impact factor: 9.139

7.  VIP antagonists enhance excitatory cholinergic neurotransmission in the human airway.

Authors:  H Aizawa; H Inoue; M Shigyo; S Takata; H Koto; K Matsumoto; N Hara
Journal:  Lung       Date:  1994       Impact factor: 2.584

8.  Neither a purine nor VIP is the mediator of inhibitory nerves of opossum oesophageal smooth muscle.

Authors:  E E Daniel; A Helmy-Elkholy; L P Jager; M S Kannan
Journal:  J Physiol       Date:  1983-03       Impact factor: 5.182

9.  The effects of vasoactive intestinal peptide (VIP) antagonists, and VIP and peptide histidine isoleucine antisera on non-adrenergic, non-cholinergic relaxations of tracheal smooth muscle.

Authors:  J L Ellis; S G Farmer
Journal:  Br J Pharmacol       Date:  1989-03       Impact factor: 8.739

10.  Apamin and nonadrenergic inhibition of guinea pig trachealis.

Authors:  M E Zacour; B Collier; J G Martin
Journal:  Agents Actions       Date:  1987-10
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