Literature DB >> 6254152

Evidence for homologous actions of pro-opiocortin products.

J M Walker, H Akil, S J Watson.   

Abstract

alpha-Melanocyte-stimulating hormone (alpha-MSH), a modified fragment of adrenocorticotropic hormone, derives from the same biosynthetic route as beta-endorphin and is stored by the same arcuate neurons. Microinjection of alpha-melanocyte-stimulating hormone and several related peptides into the periaqueductal gray matter significantly reduced responsiveness to pain and had a behavioral profile similar to that produced by beta-endorphin.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 6254152     DOI： 10.1126/science.6254152

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  5 in total

Review 1.  Synaptic changes induced by melanocortin signalling.

Authors:  Vanni Caruso; Malin C Lagerström; Pawel K Olszewski; Robert Fredriksson; Helgi B Schiöth
Journal:  Nat Rev Neurosci       Date:  2014-02       Impact factor: 34.870

2.  The relative significance of spinal and supraspinal actions in the antinociceptive effect of morphine in the dorsal horn: an evaluation of the microinjection technique.

Authors:  S L Clark; R O Edeson; R W Ryall
Journal:  Br J Pharmacol       Date:  1983-07       Impact factor: 8.739

3.  The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans.

Authors:  Jeffrey S Mogil; Sonya G Wilson; Elissa J Chesler; Andrew L Rankin; Kumar V S Nemmani; William R Lariviere; M Kristina Groce; Margaret R Wallace; Lee Kaplan; Roland Staud; Timothy J Ness; Toni L Glover; Magda Stankova; Alexander Mayorov; Victor J Hruby; Judith E Grisel; Roger B Fillingim
Journal:  Proc Natl Acad Sci U S A       Date:  2003-03-27       Impact factor: 11.205

4.  Peripheral analgesic activities of peptides related to alpha-melanocyte stimulating hormone and interleukin-1 beta 193-195.

Authors:  S Poole; A F Bristow; B B Lorenzetti; R E Das; T W Smith; S H Ferreira
Journal:  Br J Pharmacol       Date:  1992-06       Impact factor: 8.739

5.  Chlorpromazine hyperalgesia antagonizes clonidine analgesia, but enhances morphine analgesia in rats tested in a hot-water tail-flick paradigm.

Authors:  R M Gleeson; D M Atrens
Journal:  Psychopharmacology (Berl)       Date:  1982       Impact factor: 4.530
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.