Literature DB >> 6254119

N-Oxide reduction by hemoglobin, cytochrome C and ferrous ions.

G Powis, C L DeGraw.   

Abstract

Indicine N-oxide is reduced to indicine by Fe(II) ions, by enzymatically reduced cytochrome c, and by ascorbic acid in conjunction with hemin or cytochrome c. Indicine N-oxide is not reduced by native hemoglobin, but is reduced by denatured hemoglobin. Oxygen competes with indicine N-oxide for reduction by denatured hemoglobin.

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Year:  1980        PMID： 6254119

Source DB:  PubMed          Journal:  Res Commun Chem Pathol Pharmacol        ISSN： 0034-5164


  3 in total

1.  Urinary metabolites of amitriptylinoxide and amitriptyline in single-dose experiments and during continuous therapy.

Authors:  B Becher; W Fischer; Z Taneri; E Scholz; W E Müller; U Breyer-Pfaff
Journal:  Psychopharmacology (Berl)       Date:  1992       Impact factor: 4.530

Review 2.  Rationale for the use of aliphatic N-oxides of cytotoxic anthraquinones as prodrug DNA binding agents: a new class of bioreductive agent.

Authors:  L H Patterson
Journal:  Cancer Metastasis Rev       Date:  1993-06       Impact factor: 9.264

3.  Improved translation of stability for conjugated antibodies using an in vitro whole blood assay.

Authors:  Aimee Fourie-O'Donohue; Phillip Y Chu; Josefa Dela Cruz Chuh; Robert Tchelepi; Siao Ping Tsai; John C Tran; William S Sawyer; Dian Su; Carl Ng; Keyang Xu; Shang-Fan Yu; Thomas H Pillow; Jack Sadowsky; Peter S Dragovich; Yichin Liu; Katherine R Kozak
Journal:  MAbs       Date:  2020 Jan-Dec       Impact factor: 5.857
  3 in total

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