| Literature DB >> 6253991 |
Abstract
The comparative nucleotide sequences of the region of inverted terminal repetition from a representative member of group C (nononcogenic), group B (weakly oncogenic), and group A (highly oncogenic) adenoviruses are analyzed. Our data show that (i) the length of this unique region increases with the oncogenicity of the serotype, (ii) a unique homologous region--14 nucleotides long--is present exactly at the same distance from the terminus, and (iii) a hexanucleotide sequence, T-G-A-C-G-T, is present at the site where the terminal repetition diverges.Entities:
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Year: 1980 PMID: 6253991 PMCID: PMC349720 DOI: 10.1073/pnas.77.7.3831
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205