Literature DB >> 6252033

May K+ ions stimulate the formation of cyclic AMP in the brain independently on their depolarizing action?

J Krivánek.   

Abstract

The effect of potassium ions on the formation of adenosine 3',5'-monophosphate (cAMP) in the rat cerebral cortex in vivo was studied under conditions where development of spreading depression had been blocked by pretreatment of the cerebral cortex by topically applied magnesium ions. A linear relationship between potassium concentrations applied to the cortical surface and levels of cAMP has been found. Moreover, potentiation of the K+-effect by magnesium ions has been observed.

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Year:  1980        PMID： 6252033     DOI： 10.1007/bf01976117

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  6 in total

1.  A different mode of action of potassium ions and veratridine on the formation of cyclic adenosine monophosphate in the cerebral cortex.

Authors:  J Krivánek
Journal:  Neuroscience       Date:  1978       Impact factor: 3.590

2.  Adenosine 3',5'-monophosphate in rat cerebral cortex: effect of potassium ions in vivo (cortical spreading depression).

Authors:  J Krivánek
Journal:  J Neurochem       Date:  1976-02       Impact factor: 5.372

3.  Effects of diaminopropionate, deoxyadenosine, and theophylline on stimulated formation of cyclic AMP and GMP by depolarizing agents in slices of guinea-pig cerebral cortex.

Authors:  H Shimizu; Y Yamamura
Journal:  J Neurochem       Date:  1977-02       Impact factor: 5.372

4.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

5.  The effect of adenosine and adenine nucleotides on the cyclic adenosine 3', 5'-phosphate content of guinea pig cerebral cortex slices.

Authors:  A Sattin; T W Rall
Journal:  Mol Pharmacol       Date:  1970-01       Impact factor: 4.436

6.  Brain cyclic adenosine 3',5'-monophosphate during depolarization of the cerebral cortical cells in vivo.

Authors:  J Krivánek
Journal:  Brain Res       Date:  1977-01-28       Impact factor: 3.252
  6 in total

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