Literature DB >> 6252017

Evidence for a direct inhibitory effect of morphine on the secretion of posterior pituitary hormones.

B Lutz-Bucher, B Koch.   

Abstract

The effect of morphine and naloxone on vasopressin and oxytocin release from incubated neurointermediate lobe and pars nervosa of rat pituitaries were investigated. It was shown that morphine and endorphins blocked hormonal output and that this inhibitory action was reversed by naloxone. It is concluded that opiates exert a direct inhibitory influence on vasopressin and oxytocin secretions from the neurohypophysis.

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Year:  1980        PMID： 6252017     DOI： 10.1016/0014-2999(80)90470-7

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  6 in total

1.  Co-localization of arginine vasopressin- and enkephalin-like immunoreactivities in nerve cells of the rat hypothalamus.

Authors:  M Sakanaka; S Magari; N Inoue; K Lederis
Journal:  Cell Tissue Res       Date:  1990-05       Impact factor: 5.249

2.  Oxytocin under opioid antagonism leads to supralinear enhancement of social attention.

Authors:  Olga Dal Monte; Matthew Piva; Kevin M Anderson; Marios Tringides; Avram J Holmes; Steve W C Chang
Journal:  Proc Natl Acad Sci U S A       Date:  2017-05-01       Impact factor: 11.205

3.  Naloxone reduces diuretic responses induced by water, alcohol or congenital lack of vasopressin in rats.

Authors:  C Guiol; J L Montastruc; P Montastruc
Journal:  Br J Pharmacol       Date:  1984-01       Impact factor: 8.739

4.  Do opioid peptides modulate, at the level of the nerve endings, the release of neurohypophysial hormones?

Authors:  J J Nordmann; G Dayanithi; M Cazalis
Journal:  Exp Brain Res       Date:  1986       Impact factor: 1.972

5.  The effect of naloxone on vasopressin release from rat neurohypophysis incubated in vitro.

Authors:  W Knepel; D K Meyer
Journal:  J Physiol       Date:  1983-08       Impact factor: 5.182

6.  Differential effects of various opioid peptides on vasopressin and oxytocin release from the rat pituitary in vitro.

Authors:  D Maysinger; I Vermes; F Tilders; B R Seizinger; C Gramsch; V Höllt; A Herz
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1984-12       Impact factor: 3.000
  6 in total

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