| Literature DB >> 6251998 |
Abstract
Plasma concentrations of growth hormone (GH) were measured after administration of clonidine (0.5 mg/kg) to spontaneously hypertensive (SH) rats and normotensive Wistar Kyoto controls. All rats were pretreated with reserpine (10 mg/kg). The GH response to clonidine was significantly higher in SH rats than in controls, indicating that in SH rats the responsiveness of post-synaptic alpha-adrenergic structures in the hypothalamus may be increased.Entities:
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Year: 1980 PMID： 6251998 DOI： 10.3109/10641968009046428
Source DB: PubMed Journal: Clin Exp Hypertens ISSN： 0148-3927 Impact factor: 1.749