Literature DB >> 6251897

Partial purification and properties of mammalian phosphatidylglycerophosphatase.

P M MacDonald, W C McMurray.   

Abstract

The phosphatidylglycerophosphatase (EC 3.1.3.27) activity of rat liver mitochondria was investigated by assaying the conversion of 14C-labelled phosphatidylglycerophosphate to phosphatidylglycerol. The activity was associated with a mitochondrial membrane fraction and could not be released into solution employing techniques applicable to a peripheral membrane protein. The enzyme was partially purified by sonication, pH 5.0 precipitation, and gel filtration. Various ionic and nonionic detergents as well as numerous divalent cations inhibited the phosphatase. The enzyme displayed a high affinity for phosphatidylglycerophosphate.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 6251897     DOI： 10.1016/0005-2760(80)90187-3

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  8 in total

1.  N-Acetylsphingosine stimulates phosphatidylglycerolphosphate synthase activity in H9c2 cardiac cells.

Authors:  F Y Xu; S L Kelly; G M Hatch
Journal:  Biochem J       Date:  1999-02-01       Impact factor: 3.857

Review 2.  Regulation of cardiolipin biosynthesis in the heart.

Authors:  G M Hatch
Journal:  Mol Cell Biochem       Date:  1996-06-21       Impact factor: 3.396

3.  Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis.

Authors:  Ji Zhang; Ziqiang Guan; Anne N Murphy; Sandra E Wiley; Guy A Perkins; Carolyn A Worby; James L Engel; Philip Heacock; Oanh Kim Nguyen; Jonathan H Wang; Christian R H Raetz; William Dowhan; Jack E Dixon
Journal:  Cell Metab       Date:  2011-06-08       Impact factor: 27.287

4.  Biosynthesis of Phosphatidylglycerol in Isolated Mitochondria of Etiolated Mung Bean (Vigna radiata L.) Seedlings.

Authors:  R. Griebau; M. Frentzen
Journal:  Plant Physiol       Date:  1994-08       Impact factor: 8.340

5.  Stimulation of phosphatidylglycerolphosphate phosphatase activity by unsaturated fatty acids in rat heart.

Authors:  S G Cao; G M Hatch
Journal:  Lipids       Date:  1994-07       Impact factor: 1.880

6.  Cardiolipin biosynthesis in the isolated heart.

Authors:  G M Hatch
Journal:  Biochem J       Date:  1994-01-01       Impact factor: 3.857

7.  Inhibition of cardiolipin biosynthesis in the hypoxic rat heart.

Authors:  P Cheng; G M Hatch
Journal:  Lipids       Date:  1995-06       Impact factor: 1.880

8.  Biochemical characterization of acetyl-CoA:1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase in rat spleen microsomes.

Authors:  K Seyama; T Ishibashi
Journal:  Lipids       Date:  1987-03       Impact factor: 1.880
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.