Literature DB >> 6251274

Three independent isolates of feline sarcoma virus code for three distinct gag-x polyproteins.

S K Ruscetti, L P Turek, C J Sherr.   

Abstract

Cells nonproductively transformed by the Snyder-Theilen, Gardner-Arnstein, and McDonough strains of feline sarcoma virus synthesize gag-x polyproteins of 78,000, 100,000, and 180,000 daltons, respectively. These feline sarcoma virus-coded products were precipitated by antisera to polypeptides encoded by the gag gene of feline leukemia virus and by rat antisera raised to feline sarcoma virus-transformed rat tumor cells. Precipitation with rat antisera absorbed with feline leukemia virus showed that the x-portions of the three gag-x proteins were each antigenically distinct, suggesting that the src genes of the three independent isolates are not identical. Anti-x sera did not precipitate products from radiolabeled cat lymphoid tumor cells (FL74) and therefore lacked reactivity to the feline leukemia virus-induced tumor-specific antigen, FOCMA.

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Year:  1980        PMID: 6251274      PMCID: PMC288804     

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  27 in total

1.  Experimental transmission of feline fibrosarcoma to cats and dogs.

Authors:  M B Gardner; R W Rongey; P Arnstein; J D Estes; P Sarma; R J Huebner; C G Rickard
Journal:  Nature       Date:  1970-05-30       Impact factor: 49.962

2.  Transmissible feline fibrosarcoma.

Authors:  S P Snyder; G H Theilen
Journal:  Nature       Date:  1969-03-15       Impact factor: 49.962

3.  Replication of cat leukemia virus in cell suspension cultures.

Authors:  G H Theilen; T G Kawakami; J D Rush; R J Munn
Journal:  Nature       Date:  1969-05-10       Impact factor: 49.962

4.  A transmissible virus-induced lymphocytic leukemia of the cat.

Authors:  C G Rickard; J E Post; F Noronha; L M Barr
Journal:  J Natl Cancer Inst       Date:  1969-06       Impact factor: 13.506

5.  Characterization of a protein found in cells infected with the spleen focus-forming virus that shares immunological cross-reactivity with the gp70 found in mink cell focus-inducing virus particles.

Authors:  S K Ruscetti; D Linemeyer; J Feild; D Troxler; E M Scolnick
Journal:  J Virol       Date:  1979-06       Impact factor: 5.103

6.  p21 of Kirsten murine sarcoma virus is thermolabile in a viral mutant temperature sensitive for the maintenance of transformation.

Authors:  T Y Shih; M O Weeks; H A Young; E M Scolnick
Journal:  J Virol       Date:  1979-08       Impact factor: 5.103

7.  Restriction endonuclease mapping of unintegrated proviral DNA of Snyder-Theilen feline sarcoma virus: localization of sarcoma-specific sequences.

Authors:  C J Sherr; L A Fedele; L Donner; L P Turek
Journal:  J Virol       Date:  1979-12       Impact factor: 5.103

8.  Polymorphism of avian sarcoma virus src proteins.

Authors:  K Beemon; T Hunter; B M Sefton
Journal:  J Virol       Date:  1979-04       Impact factor: 5.103

9.  Nature and distribution of feline sarcoma virus nucleotide sequences.

Authors:  A E Frankel; J H Gilbert; K J Porzig; E M Scolnick; S A Aaronson
Journal:  J Virol       Date:  1979-06       Impact factor: 5.103

10.  Molecular cloning of Snyder-Theilen feline leukemia and sarcoma viruses: comparative studies of feline sarcoma virus with its natural helper virus and with Moloney murine sarcoma virus.

Authors:  C J Sherr; L A Fedele; M Oskarsson; J Maizel; G Vande Woude
Journal:  J Virol       Date:  1980-04       Impact factor: 5.103

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  29 in total

1.  Tyrosine phosphorylations in vivo associated with v-fms transformation.

Authors:  D K Morrison; P J Browning; M F White; T M Roberts
Journal:  Mol Cell Biol       Date:  1988-01       Impact factor: 4.272

2.  Antibodies of predetermined specificity detect two retroviral oncogene products and inhibit their kinase activities.

Authors:  S Sen; R A Houghten; C J Sherr; A Sen
Journal:  Proc Natl Acad Sci U S A       Date:  1983-03       Impact factor: 11.205

3.  Human c-fms proto-oncogene: comparative analysis with an abnormal allele.

Authors:  J S Verbeek; A J Roebroek; A M van den Ouweland; H P Bloemers; W J Van de Ven
Journal:  Mol Cell Biol       Date:  1985-02       Impact factor: 4.272

4.  Retrovirus antigens in brains of mice with scrapie- and murine leukemia virus-induced spongiform encephalopathy.

Authors:  P M Hoffman; O M Pitts; R G Rohwer; D C Gajdusek; S K Ruscetti
Journal:  Infect Immun       Date:  1982-10       Impact factor: 3.441

5.  Human gene (c-fes) related to the onc sequences of Snyder-Theilen feline sarcoma virus.

Authors:  G Franchini; E P Gelmann; R Dalla-Favera; R C Gallo; F Wong-Staal
Journal:  Mol Cell Biol       Date:  1982-08       Impact factor: 4.272

6.  Rat sarcoma virus: further analysis of individual viral isolates and the gene product.

Authors:  H A Young; S Rasheed; R Sowder; C V Benton; L E Henderson
Journal:  J Virol       Date:  1981-04       Impact factor: 5.103

7.  Retrovirus-encoded transformation-specific polyproteins: expression coordinated with malignant phenotype in cells from different germ layers.

Authors:  A P Chen; M Essex; J A Shadduck; J Y Niederkorn; D Albert
Journal:  Proc Natl Acad Sci U S A       Date:  1981-06       Impact factor: 11.205

8.  Structure of the feline c-fes/fps proto-oncogene: genesis of a retroviral oncogene.

Authors:  A J Roebroek; J A Schalken; C Onnekink; H P Bloemers; W J Van de Ven
Journal:  J Virol       Date:  1987-06       Impact factor: 5.103

9.  Transformation-defective mutants of feline sarcoma virus which express a product of the viral src gene.

Authors:  L Donner; L P Turek; S K Ruscetti; L A Fedele; C J Sherr
Journal:  J Virol       Date:  1980-07       Impact factor: 5.103

10.  Transformation-defective mutants of Snyder-Theilen feline sarcoma virus lack tyrosine-specific protein kinase activity.

Authors:  M Barbacid; L Donner; S K Ruscetti; C J Sherr
Journal:  J Virol       Date:  1981-07       Impact factor: 5.103

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