Literature DB >> 6250468

Inhibition of herpes simplex virus multiplication by the pokeweed antiviral protein.

G M Aron, J D Irvin.   

Abstract

The pokeweed antiviral protein inhibited the multiplication of herpes simplex virus type 1 in cell culture. The extent of antiviral activity was proportional to the length of time that the antiviral protein was present postinfection. The results demonstrate that the continued presence of the pokeweed antiviral protein is necessary for the maximum inhibition of virus yields.

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Year:  1980        PMID： 6250468      PMCID： PMC283924          DOI： 10.1128/AAC.17.6.1032

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  7 in total

1.  Purification and partial characterization of the antiviral protein from Phytolacca americana which inhibits eukaryotic protein synthesis.

Authors:  J D Irvin
Journal:  Arch Biochem Biophys       Date:  1975-08       Impact factor: 4.013

2.  Inhibition of poliovirus replication by a plant antiviral peptide.

Authors:  M A Ussery; J D Irvin; B Hardesty
Journal:  Ann N Y Acad Sci       Date:  1977-03-04       Impact factor: 5.691

3.  Spectrum of human cytomegalovirus complement-fixing antigens.

Authors:  G R Dreesman; M Benyesh-Melnick
Journal:  J Immunol       Date:  1967-12       Impact factor: 5.422

4.  The effect of an antiviral peptide on the ribosomal reactions of the peptide elongation enzymes, EF-I and EF-II.

Authors:  T G Obrig; J D Irvin; B Hardesty
Journal:  Arch Biochem Biophys       Date:  1973-04       Impact factor: 4.013

5.  Isolation and characterization of a virus inhibitor from Phytolacca americana.

Authors:  S D Wyatt; R J Shepherd
Journal:  Phytopathology       Date:  1969-12       Impact factor: 4.025

6.  Purification and properties of a second antiviral protein from Phytolacca americana which inactivates eukaryotic ribosomes.

Authors:  J D Irvin; T Kelly; J D Robertus
Journal:  Arch Biochem Biophys       Date:  1980-04-01       Impact factor: 4.013

7.  The inhibition of infection by cucumber mosaic virus and influenza virus by extracts from Phytolacca americana.

Authors:  J A Tomlinson; V M Walker; T H Flewett; G R Barclay
Journal:  J Gen Virol       Date:  1974-02       Impact factor: 3.891
  7 in total
  20 in total

1.  Inhibition of pokeweed antiviral protein (PAP) by turnip mosaic virus genome-linked protein (VPg).

Authors:  Artem V Domashevskiy; Hiroshi Miyoshi; Dixie J Goss
Journal:  J Biol Chem       Date:  2012-07-06       Impact factor: 5.157

2.  A novel mechanism for inhibition of translation by pokeweed antiviral protein: depurination of the capped RNA template.

Authors:  K A Hudak; P Wang; N E Tumer
Journal:  RNA       Date:  2000-03       Impact factor: 4.942

3.  C-terminal deletion mutant of pokeweed antiviral protein inhibits viral infection but does not depurinate host ribosomes.

Authors:  N E Tumer; D J Hwang; M Bonness
Journal:  Proc Natl Acad Sci U S A       Date:  1997-04-15       Impact factor: 11.205

4.  Safety, activity, and pharmacokinetics of GLQ223 in patients with AIDS and AIDS-related complex.

Authors:  J O Kahn; K J Gorelick; G Gatti; C J Arri; J D Lifson; J G Gambertoglio; A Bostrom; R Williams
Journal:  Antimicrob Agents Chemother       Date:  1994-02       Impact factor: 5.191

5.  A non-toxic pokeweed antiviral protein mutant inhibits pathogen infection via a novel salicylic acid-independent pathway.

Authors:  O Zoubenko; K Hudak; N E Tumer
Journal:  Plant Mol Biol       Date:  2000-09       Impact factor: 4.076

6.  Anti-human immunodeficiency virus type 1 activity of an anti-CD4 immunoconjugate containing pokeweed antiviral protein.

Authors:  A Erice; H H Balfour; D E Myers; V L Leske; K J Sannerud; V Kuebelbeck; J D Irvin; F M Uckun
Journal:  Antimicrob Agents Chemother       Date:  1993-04       Impact factor: 5.191

7.  Ribosome-inactivating proteins from the seeds of Saponaria officinalis L. (soapwort), of Agrostemma githago L. (corn cockle) and of Asparagus officinalis L. (asparagus), and from the latex of Hura crepitans L. (sandbox tree).

Authors:  F Stirpe; A Gasperi-Campani; L Barbieri; A Falasca; A Abbondanza; W A Stevens
Journal:  Biochem J       Date:  1983-12-15       Impact factor: 3.857

8.  Effect of ribosome-inactivating proteins on virus-infected cells. Inhibition of virus multiplication and of protein synthesis.

Authors:  L Foà-Tomasi; G Campadelli-Fiume; L Barbieri; F Stirpe
Journal:  Arch Virol       Date:  1982       Impact factor: 2.574

9.  Isolation and analysis of a genomic clone encoding a pokeweed antiviral protein.

Authors:  J Kataoka; N Habuka; C Masuta; M Miyano; A Koiwai
Journal:  Plant Mol Biol       Date:  1992-12       Impact factor: 4.076

10.  Purification and partial characterization of another form of the antiviral protein from the seeds of Phytolacca americana L. (pokeweed).

Authors:  L Barbieri; G M Aron; J D Irvin; F Stirpe
Journal:  Biochem J       Date:  1982-04-01       Impact factor: 3.857
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