Literature DB >> 6250219

J genes for heavy chain immunoglobulins of mouse.

N Newell, J E Richards, P W Tucker, F R Blattner.   

Abstract

A 15,8-kilobase pair fragment of BALB/c mouse liver DNA, cloned in the Charon 4A lambda phage vector system, was shown to contain the mu heavy chain constant region (CHmu) gene for the mouse immunoglobulin M. In addition, this fragment of DNA contains at least two J genes, used to code for the carboxyl terminal portion of heavy chain variable regions. These genes are located in genomic DNA about eight kilobase pairs to the 5' side of the CHmu gene. The complete nucleotide sequence of a 1120-base pair stretch of DNA that includes the two J genes has been determined.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 6250219     DOI： 10.1126/science.6250219

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  26 in total

Review 1.  Mouse chromosome 12.

Authors:  P D'Eustachio
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

2.  Allelic polymorphism of mouse Igh-J locus, which encodes immunoglobulin heavy chain joining (JH) segments.

Authors:  M L Solin; M Kaartinen
Journal:  Immunogenetics       Date:  1992       Impact factor: 2.846

3.  Molecular analysis of neonatal IgA expression: implications for class switching, allelic polymorphism and somatic mutation.

Authors:  S L Jones; J M Teale; S C Riley; N R Klinman; P W Tucker
Journal:  Immunol Res       Date:  1990       Impact factor: 2.829

4.  Hamster cDNA homologs to the mouse immunoglobulin IgG2 constant and Igh-VH10 genes.

Authors:  M Collins; M J Whitters
Journal:  Immunogenetics       Date:  1995       Impact factor: 2.846

5.  Frequent lambda light chain gene rearrangement and expression in a Ly-1 B lymphoma with a productive kappa chain allele.

Authors:  R R Hardy; J L Dangl; K Hayakawa; G Jager; L A Herzenberg; L A Herzenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1986-03       Impact factor: 11.205

6.  High rate of somatic point mutation in vitro in and near the variable-region segment of an immunoglobulin heavy chain gene.

Authors:  J Meyer; H M Jäck; N Ellis; M Wabl
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205

7.  Homologous recombination in hybridoma cells: heavy chain chimeric antibody produced by gene targeting.

Authors:  H P Fell; S Yarnold; I Hellström; K E Hellström; K R Folger
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205

8.  A measure of the similarity of sets of sequences not requiring sequence alignment.

Authors:  B E Blaisdell
Journal:  Proc Natl Acad Sci U S A       Date:  1986-07       Impact factor: 11.205

9.  Physical linkage of the constant region genes for immunoglobulins lambda I and lambda III.

Authors:  J Miller; A Bothwell; U Storb
Journal:  Proc Natl Acad Sci U S A       Date:  1981-06       Impact factor: 11.205

10.  Illegitimate recombination generates a class switch from C mu to C delta in an IgD-secreting plasmacytoma.

Authors:  A C Gilliam; A Shen; J E Richards; F R Blattner; J F Mushinski; P W Tucker
Journal:  Proc Natl Acad Sci U S A       Date:  1984-07       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.