| Literature DB >> 6250218 |
R T Savoy-Moore, N B Schwartz, J A Duncan, J C Marshall.
Abstract
The binding of [6-alanine]gonadotropin-releasing hormone to pituitary plasma membranes increased threefold between metestrus and early proestrus in female rats. Receptor numbers fell rapidly on the afternoon of proestrus coincident with the preovulatory gonadotropin surge. The numbers of receptors for gonadotropin-releasing hormone were positively correlated with concentrations of estradiol in serum; this pattern may be a necessary component of increased pituitary sensitivty to gonadotropin-releasing hormone observed during proestrus.Entities:
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Year: 1980 PMID: 6250218 DOI: 10.1126/science.6250218
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728