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Literature DB >> 6249476

Production of tumors in hamsters by cells of a pig uterine tube line.

A M Bouillant, A Bundza, P Genest, A S Greig.

Abstract

Tumorigenicity was investigated in a pig established cell line continuously subcultured more than 400 times. Tumors were not found in hamsters' cheek pouches inoculated with cells from the first 200 subcultures. Fibroma developed in five out of 13 animals (9/26 pouches) inoculated with cells of the 313th and 314th subcultures. Two chromosome markers were found in the 290th subculture, in the 313th subculture inoculum and in tumor cells.

Entities: Disease Species

Mesh：

Year: 1980 PMID： 6249476 PMCID： PMC1320037

Source DB: PubMed Journal: Can J Comp Med ISSN： 0008-4050

25 in total

1. Biological characterization of a cell line derived from the pig oviduct.

Authors: A Bouliant; A S Greig; P Genest
Journal: In Vitro Date: 1973 Sep-Oct

2. C-type particles produced by a permanent cell line from a leukemic pig. I. Origin and properties of the host cells and some evidence for the occurrence of C-type-like particles.

Authors: H Strandström; P Veijalainen; V Moennig; G Hunsmann; H Schwarz; W Schäfer
Journal: Virology Date: 1974-01 Impact factor: 3.616

10. Growth characteristics of virus-transformed cells. Maximum population density, inhibition by normal cells, serum requirement, growth in soft agar, and xenogeneic transplantability.

Authors: H Eagle; G E Foley; H Koprowski; H Lazarus; E M Levine; R A Adams
Journal: J Exp Med Date: 1970-04-01 Impact factor: 14.307

1 in total

1. Nontumoral, benign ad malignant stages of transformation of a diploid pig cell line. A review.

Authors: A M Bouillant; P Genest; A S Greig
Journal: Can J Comp Med Date: 1981-07

1 in total

Production of tumors in hamsters by cells of a pig uterine tube line.

1. Biological characterization of a cell line derived from the pig oviduct.

2. C-type particles produced by a permanent cell line from a leukemic pig. I. Origin and properties of the host cells and some evidence for the occurrence of C-type-like particles.

3. C-type virus particles in pig kidney cell lines.

4. RNA-dependent DNA polymerase in virions of RNA tumour viruses.

5. Virus-like particles occurring in cultures of stable pig kidney cell lines. Brief report.

Review 6. "Spontaneous" neoplastic transformation of cells in vitro: some facts and theories.

7. Development of invasive tumors in the "nude" mouse after injection of cultured human melanoma cells.

8. Anchorage and growth regulation in normal and virus-transformed cells.

9. Mammalian cells in culture frequently release type C viruses.

10. Growth characteristics of virus-transformed cells. Maximum population density, inhibition by normal cells, serum requirement, growth in soft agar, and xenogeneic transplantability.

1. Nontumoral, benign ad malignant stages of transformation of a diploid pig cell line. A review.