Literature DB >> 6249431

An erythropoietic stimulating factor similar to erythropoietin released by macrophages after treatment with silica.

I N Rich, W Heit, B Kubanek.   

Abstract

An erythropoietic stimulating factor (ESF) can be detected in the supernatant from fetal liver and adult bone marrow and spleen cells when preincubated with the macrophage-specific cytotoxic agent, silica. Stimulation is observed in 12-day fetal liver CFU-E cultures in the absence of added erythropoietin (Ep). The concentration of ESF in the supernatant added to CFU-E cultures is dependent on the preincubated cell dose and the volume added. The stimulating activity is abolished when mice are hypertransfused and increased above normal values when mice are bled. A concentrated silica-treated spleen supernatant was able to stimulate erythropoiesis in the polycythemic mouse bioassay. It is concluded that the ESF is similar, if not identical, to Ep.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 6249431     DOI： 10.1007/bf01025584

Source DB:  PubMed          Journal:  Blut        ISSN： 0006-5242


  9 in total

1.  ERYTHROPOIESIS IN ANEPHRIC MAN.

Authors:  D G NATHAN; E SCHUPAK; F STOHLMAN; J P MERRILL
Journal:  J Clin Invest       Date:  1964-11       Impact factor: 14.808

2.  Bio-assay of erythropoietin in mice made polycythaemic by exposure to air at a reduced pressure.

Authors:  P M COTES; D R BANGHAM
Journal:  Nature       Date:  1961-09-09       Impact factor: 49.962

3.  Identification of erythropoietin producing cells in fetal mouse liver cultures.

Authors:  D F Gruber; J R Zucali; E A Mirand
Journal:  Exp Hematol       Date:  1977-09       Impact factor: 3.084

4.  The ontogeny of erythropoiesis in the mouse detected by the erythroid colony-forming technique. I. Hepatic and maternal erythropoiesis.

Authors:  I N Rich; B Kubanek
Journal:  J Embryol Exp Morphol       Date:  1979-04

5.  The macrophage in allograft immunity. I. Effects of silica as a specific macrophage toxin.

Authors:  N N Pearsall; R S Weiser
Journal:  J Reticuloendothel Soc       Date:  1968-04

6.  Erythroid colony formation in cultures of mouse and human bone marrow: analysis of the requirement for erythropoietin by gel filtration and affinity chromatography on agarose-concanavalin A.

Authors:  N N Iscove; F Sieber; K H Winterhalter
Journal:  J Cell Physiol       Date:  1974-04       Impact factor: 6.384

7.  Increased erythropoietin production in anephric rats with hyperplasia of the reticuloendothelial system induced by colloidal carbon or zymosan.

Authors:  C Peschle; G Marone; A Genovese; I A Rappaport; M Condorelli
Journal:  Blood       Date:  1976-02       Impact factor: 22.113

8.  Erythroid colony formation (CFUe) in fetal liver and adult bone marrow and spleen from the mouse.

Authors:  I N Rich; B Kubanek
Journal:  Blut       Date:  1976-09

9.  An examination of the cytotoxic effects of silica on macrophages.

Authors:  A C Allison; J S Harington; M Birbeck
Journal:  J Exp Med       Date:  1966-08-01       Impact factor: 14.307
  9 in total
  2 in total

1.  Perioperative plasma erythropoietin levels in hip arthroplasty.

Authors:  A Lorentz; K U Eckardt; P M Osswald; C Kruse
Journal:  Ann Hematol       Date:  1994-03       Impact factor: 3.673

2.  Systemic inhibition of NF-kappaB activation protects from silicosis.

Authors:  Michelangelo Di Giuseppe; Federica Gambelli; Gary W Hoyle; Giuseppe Lungarella; Sean M Studer; Thomas Richards; Sam Yousem; Ken McCurry; James Dauber; Naftali Kaminski; George Leikauf; Luis A Ortiz
Journal:  PLoS One       Date:  2009-05-25       Impact factor: 3.240
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.