Literature DB >> 6248880

Identification of a proviral genome associated with avian myeloblastic leukemia.

L M Souza, M C Komaromy, M A Baluda.   

Abstract

We have identified and isolated a presumptive leukemogenic provirus from myeloblasts of a chicken in which leukemia had been induced by avian myeloblastosis virus (AMV). Leukemic myeloblasts isolated from peripheral blood or from converted yolk sac cultures of various strains of chickens, regardless of the endogenous proviral content or AMV pseudotype used for infection, contain an EcoRI 2.2-megadalton (MDaI) and a HindIII 2.6-MDal proviral fragment. A proviral genome flanked by chicken DNA sequences on either side and containing both the EcoRI 2.2-MDal and the HindIII 2.6-MDal fragments was inserted by molecular recombination into lambda phage Charon 4A and then cloned. This presumptive AMV proviral genome has a mass of approximately 4.9 MDal and contains terminal redundancies with respect to 3' viral RNA sequences.

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Year:  1980        PMID： 6248880      PMCID： PMC349535          DOI： 10.1073/pnas.77.5.3004

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  16 in total

1.  The RNA of avian acute leukemia virus MC29.

Authors:  P H Duesberg; K Bister; P K Vogt
Journal:  Proc Natl Acad Sci U S A       Date:  1977-10       Impact factor: 11.205

2.  Mapping unintegrated avian sarcoma virus DNA: termini of linear DNA bear 300 nucleotides present once or twice in two species of circular DNA.

Authors:  P R Shank; S H Hughes; H J Kung; J E Majors; N Quintrell; R V Guntaka; J M Bishop; H E Varmus
Journal:  Cell       Date:  1978-12       Impact factor: 41.582

3.  Screening lambdagt recombinant clones by hybridization to single plaques in situ.

Authors:  W D Benton; R W Davis
Journal:  Science       Date:  1977-04-08       Impact factor: 47.728

4.  Spontaneous segregation of nontransforming viruses from cloned sarcoma viruses.

Authors:  P K Vogt
Journal:  Virology       Date:  1971-12       Impact factor: 3.616

5.  Studies on single foci of hematopoietic cells transformed by avian myeloblastosis virus.

Authors:  C Moscovici; M Zanetti
Journal:  Virology       Date:  1970-09       Impact factor: 3.616

6.  The oncogenic effects of nontransforming viruses from avian myeloblastosis virus.

Authors:  R E Smith; C Moscovici
Journal:  Cancer Res       Date:  1969-07       Impact factor: 12.701

7.  Effects of genetic cellular resistance on cell transformation and virus replication in chicken hematopoietic cell cultures infected with avian myeloblastosis virus (BAI-A).

Authors:  C Moscovici; P K Vogt
Journal:  Virology       Date:  1968-08       Impact factor: 3.616

8.  The isolation of structural genes from libraries of eucaryotic DNA.

Authors:  T Maniatis; R C Hardison; E Lacy; J Lauer; C O'Connell; D Quon; G K Sim; A Efstratiadis
Journal:  Cell       Date:  1978-10       Impact factor: 41.582

9.  Cloning human fetal gamma globin and mouse alpha-type globin DNA: preparation and screening of shotgun collections.

Authors:  F R Blattner; A E Blechl; K Denniston-Thompson; H E Faber; J E Richards; J L Slightom; P W Tucker; O Smithies
Journal:  Science       Date:  1978-12-22       Impact factor: 47.728

10.  Homology between avian oncornavirus RNAs and DNA from several avian species.

Authors:  M Shoyab; M A Baluda
Journal:  J Virol       Date:  1975-12       Impact factor: 5.103
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  16 in total

1.  Hematopoietic lineage-specific heterogeneity in the 5'-terminal region of the chicken proto-myb transcript.

Authors:  W K Kim; M A Baluda
Journal:  Mol Cell Biol       Date:  1989-09       Impact factor: 4.272

2.  Differential effects of transforming avian RNA tumor viruses on avian macrophages.

Authors:  E M Durban; D Boettiger
Journal:  Proc Natl Acad Sci U S A       Date:  1981-06       Impact factor: 11.205

3.  Isolation and characterization of the complete chicken beta-globin gene region: frequent deletion of the adult beta-globin genes in lambda.

Authors:  B Villeponteau; H Martinson
Journal:  Nucleic Acids Res       Date:  1981-08-11       Impact factor: 16.971

4.  Nucleotide sequence analysis of the long terminal repeat of avian myeloblastosis virus and adjacent host sequences.

Authors:  K E Rushlow; J A Lautenberger; E P Reddy; L M Souza; M A Baluda; J G Chirikjian; T S Papas
Journal:  J Virol       Date:  1982-06       Impact factor: 5.103

5.  Organization of chicken DNA sequences homologous to the transforming gene of avian myeloblastosis virus. II. Isolation and characterization of lambda proto-amv DNA recombinant clones from a library of leukemic chicken DNA.

Authors:  B Perbal; J M Cline; R L Hillyard; M A Baluda
Journal:  J Virol       Date:  1983-03       Impact factor: 5.103

6.  Proposal for naming host cell-derived inserts in retrovirus genomes.

Authors:  J M Coffin; H E Varmus; J M Bishop; M Essex; W D Hardy; G S Martin; N E Rosenberg; E M Scolnick; R A Weinberg; P K Vogt
Journal:  J Virol       Date:  1981-12       Impact factor: 5.103

7.  Avian myeloblastosis provirus cloned in a lambda bacteriophage is leukemogenic.

Authors:  R F Silva; B Perbal; D G Bergmann; M A Baluda
Journal:  J Virol       Date:  1982-10       Impact factor: 5.103

8.  Identification of the avian myeloblastosis virus genome. II. Restriction endonuclease analysis of DNA from lambda proviral recombinants and leukemic myeoblast clones.

Authors:  L M Souza; M J Briskin; R L Hillyard; M A Baluda
Journal:  J Virol       Date:  1980-11       Impact factor: 5.103

9.  Cellular sequences are present in the presumptive avian myeloblastosis virus genome.

Authors:  L M Souza; J N Strommer; R L Hillyard; M C Komaromy; M A Baluda
Journal:  Proc Natl Acad Sci U S A       Date:  1980-09       Impact factor: 11.205

10.  Identification of the avian myeloblastosis virus genome. I. Identification of restriction endonuclease fragments associated with acute myeloblastic leukemia.

Authors:  L M Souza; M A Baluda
Journal:  J Virol       Date:  1980-11       Impact factor: 5.103
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