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Literature DB >> 6248877

In vitro construction of a B-tropic virus by recombination: B-tropism is a cryptic phenotype of xenotropic murine retroviruses.

J W Gautsch, J H Elder, F C Jensen, R A Lerner.

Abstract

A B-tropic virus was isolated in vitro from the progeny of mouse cells doubly infected with N-tropic and xenotropic murine leukemia viruses. Biological and structural evidence is presented suggesting that the phenotypically silent structural marker for B-tropism, expressed by the xenotropic virus p30, was transferred to an N-ecotropic virus via recombination, thus resulting in the expression of a B-ecotropic murine leukemia virus.

Entities: Gene Species

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Year: 1980 PMID： 6248877 PMCID： PMC349532 DOI： 10.1073/pnas.77.5.2989

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

33 in total

1. Murine sarcoma virus pseudotypes acquire a determinant specifying N or B tropism from leukaemia virus during rescue.

Authors: R H Bassin; B I Gerwin; G Duran-Troise; S Gisselbrecht; A Rein
Journal: Nature Date: 1975-07-17 Impact factor: 49.962

2. Radioiodination of proteins in single polyacrylamide gel slices. Tryptic peptide analysis of all the major members of complex multicomponent systems using microgram quantities of total protein.

Authors: J H Elder; R A Pickett; J Hampton; R A Lerner
Journal: J Biol Chem Date: 1977-09-25 Impact factor: 5.157

3. A short-term quantitative XC assay for murine leukemia virus.

Authors: J W Gautsch; H Meier
Journal: Virology Date: 1976-07-15 Impact factor: 3.616

4. Structural markers on core protein p30 of murine leukemia virus: functional correlation with Fv-1 tropism.

Authors: J W Gautsch; J H Elder; J Schindler; F C Jensen; R A Lerner
Journal: Proc Natl Acad Sci U S A Date: 1978-09 Impact factor: 11.205

5. Separation of murine cellular and murine leukaemia virus DNA polymerases.

Authors: J Ross; E M Scolnick; G J Todaro; S A Aaronson
Journal: Nat New Biol Date: 1971-06-09

6. Murine sarcoma virus defectiveness. Viral polymerase expression murine and nonmurine host cells transformed by S+L-type murine sarcoma virus.

Authors: P T Peeples; B I Gerwin; A G Papageorge; S G Smith
Journal: Virology Date: 1975-10 Impact factor: 3.616

7. Segregation of genetic information for a B-tropic leukemia virus with the structural locus for BALB:virus-1.

Authors: K C Robbins; C D Cabradilla; J R Stephenson; S A Aaronson
Journal: Proc Natl Acad Sci U S A Date: 1977-07 Impact factor: 11.205

8. Six-NB-tropic murine leukemia viruses derived from a B-tropic virus of BALB/c have altered p30.

Authors: N Hopkins; J Schindler; R Hynes
Journal: J Virol Date: 1977-01 Impact factor: 5.103

9. Host-range restrictions of murine leukemia viruses in mouse embryo cell cultures.

Authors: J W Hartley; W P Rowe; R J Huebner
Journal: J Virol Date: 1970-02 Impact factor: 5.103

10. Studies of genetic transmission of murine leukemia virus by AKR mice. I. Crosses with Fv-1 n strains of mice.

Authors: W P Rowe
Journal: J Exp Med Date: 1972-11-01 Impact factor: 14.307

15 in total

1. Development and characterization of an Fv-1-sensitive retrovirus-packaging system: single-hit titration kinetics observed in restrictive cells.

Authors: L R Boone; C L Innes; P L Glover; E Linney
Journal: J Virol Date: 1989-06 Impact factor: 5.103

2. Biochemical analysis of the p30's of N-, B-, and B leads to NB-tropic murine leukemia viruses of BALB/c origin.

Authors: J Schindler; J W Gautsch; R A Lerner; N Hopkins
Journal: J Virol Date: 1981-09 Impact factor: 5.103

3. Nucleotide sequences of gag-pol regions that determine the Fv-1 host range property of BALB/c N-tropic and B-tropic murine leukemia viruses.

Authors: C Y Ou; L R Boone; C K Koh; R W Tennant; W K Yang
Journal: J Virol Date: 1983-12 Impact factor: 5.103

4. Fv-1 host restriction of Friend leukemia virus: oligonucleotide analysis of host range variants.

Authors: S Duttagupta; R Soeiro
Journal: J Virol Date: 1981-04 Impact factor: 5.103

5. Endogenous xenotropic murine leukemia virus-related sequences map to chromosomal regions encoding mouse lymphocyte antigens.

Authors: J C Wejman; B A Taylor; N A Jenkins; N G Copeland
Journal: J Virol Date: 1984-04 Impact factor: 5.103

6. Spontaneous and induced leukemias of myeloid origin in recombinant inbred BXH mice.

Authors: H G Bedigian; D A Johnson; N A Jenkins; N G Copeland; R Evans
Journal: J Virol Date: 1984-09 Impact factor: 5.103

7. Fv-1 determinants in xenotropic murine leukemia viruses studied with biological assay systems: Isolation of xenotropic virus with N-tropic Fv-1 activity in the cryptic form.

Authors: K Sakai; H Narita; A Adachi; S Tsuruta; T Yorifuji; A Ishimoto
Journal: J Virol Date: 1982-04 Impact factor: 5.103

8. Ecotropic murine leukemia virus DNA content of normal and lymphomatous tissues of BXH-2 recombinant inbred mice.

Authors: N A Jenkins; N G Copeland; B A Taylor; H G Bedigian; B K Lee
Journal: J Virol Date: 1982-05 Impact factor: 5.103

9. Fv-1 N- and B-tropism-specific sequences in murine leukemia virus and related endogenous proviral genomes.

Authors: L R Boone; P L Glover; C L Innes; L A Niver; M C Bondurant; W K Yang
Journal: J Virol Date: 1988-08 Impact factor: 5.103

10. Analysis of wild-derived mice for Fv-1 and Fv-2 murine leukemia virus restriction loci: a novel wild mouse Fv-1 allele responsible for lack of host range restriction.

Authors: C A Kozak
Journal: J Virol Date: 1985-08 Impact factor: 5.103