Literature DB >> 6247874

Binding of thyrotrophin to low molecular weight fragments of human thyroid membranes.

F Adlkofer, P Kotulla, H Schleusener.   

Abstract

The LATS absorbing activity from thyroid homogenates which is associated with the soluble thyroid fraction (4S-LAA) binds TSH in addition to LATS. This may indicate that 4S-LAA originates from the receptor sites for TSH at the thyroid cell surface. The affinity of 4S-LAA for TSH is much lower than that of thyroid membranes suggesting that 4S-LAA represents incomplete receptor sites or receptor sites which are altered in their structure.

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Year:  1980        PMID: 6247874     DOI: 10.1530/acta.0.0940058

Source DB:  PubMed          Journal:  Acta Endocrinol (Copenh)        ISSN: 0001-5598


  2 in total

Review 1.  The thyrotrophin receptor.

Authors:  S W Manley; A Knight; D D Adams
Journal:  Springer Semin Immunopathol       Date:  1982

2.  A Modifying Autoantigen in Graves' Disease.

Authors:  Rauf Latif; Mihaly Mezei; Syed A Morshed; Risheng Ma; Rachel Ehrlich; Terry F Davies
Journal:  Endocrinology       Date:  2019-05-01       Impact factor: 4.736

  2 in total

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