Literature DB >> 6247374

Alcohol potentiation of isoproterenol-stimulated cyclic AMP accumulation in rat parotid.

J F Harper, G Brooker.   

Abstract

The ability of beta-adrenergic agonists to elevate rat parotid cyclic AMP concentrations is potentiated greatly by certain organic solvents. Propanol was found to be more effective than other tested solvents. Propanol stimulated adenylate cyclase and inhibited low Km cyclic AMP phosphodiesterase activities however the magnitude of effect upon these enzyme activities probably does not account for the potentiation of cyclic AMP accumulation observed in intact cells.

Entities:  

Mesh:

Substances:

Year:  1980        PMID: 6247374

Source DB:  PubMed          Journal:  J Cyclic Nucleotide Res        ISSN: 0095-1544


  4 in total

1.  Effect of ethyl alcohol on the TSH-receptor-cyclase system in thyroid and nonthyroid tissues.

Authors:  O H Clark; P L Gerend
Journal:  World J Surg       Date:  1986-10       Impact factor: 3.352

2.  A Ca2+-linked increase in coupled cAMP synthesis and hydrolysis is an early event in cholinergic and beta-adrenergic stimulation of parotid secretion.

Authors:  M A Deeg; R M Graeff; T F Walseth; N D Goldberg
Journal:  Proc Natl Acad Sci U S A       Date:  1988-11       Impact factor: 11.205

3.  Ethanol regulation of adenosine receptor-stimulated cAMP levels in a clonal neural cell line: an in vitro model of cellular tolerance to ethanol.

Authors:  A S Gordon; K Collier; I Diamond
Journal:  Proc Natl Acad Sci U S A       Date:  1986-04       Impact factor: 11.205

4.  Defective beta adrenergic response of cystic fibrosis sweat glands in vivo and in vitro.

Authors:  K Sato; F Sato
Journal:  J Clin Invest       Date:  1984-06       Impact factor: 14.808

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.