Literature DB >> 6247193

Stimulation of macromolecular synthesis by endotoxin-treated 3T6 fibroblasts.

J J Aleo.   

Abstract

The interaction of endotoxin with cultured fibroblasts resulted in a depression of cellular proliferation and an increased synthesis of macromolecules, namely collagenous and non-collagenous proteins. The collagen salt-soluble fraction was increased at the expense of the insoluble fraction, and both the salt-soluble fraction and collagen secreted into the medium was underhydroxylated.

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Year:  1980        PMID: 6247193     DOI: 10.1007/bf01965790

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  8 in total

1.  Amino acid metabolism in mammalian cell cultures.

Authors:  H EAGLE
Journal:  Science       Date:  1959-08-21       Impact factor: 47.728

2.  EXPERIMENTAL GINGIVITIS IN MAN.

Authors:  H LOE; E THEILADE; S B JENSEN
Journal:  J Periodontol       Date:  1965 May-Jun       Impact factor: 6.993

3.  A method for the simultaneous measurement of the radioactivity of proline-C14 and hydroxyproline-C14 in biological materials.

Authors:  B PETERKOFSKY; D J PROCKOP
Journal:  Anal Biochem       Date:  1962-11       Impact factor: 3.365

4.  Collagen synthesis by lathyrogen-treated 3T6 fibroblasts.

Authors:  J J Aleo; R Novack; E Levy
Journal:  Connect Tissue Res       Date:  1974       Impact factor: 3.417

5.  Experimental gingivitis in man. II. A longitudinal clinical and bacteriological investigation.

Authors:  E Theilade; W H Wright; S B Jensen; H Löe
Journal:  J Periodontal Res       Date:  1966       Impact factor: 4.419

6.  The effect of bacterial products on synovial fibroblast function: hypermetabolic changes induced by endotoxin.

Authors:  R B Buckingham; C W Castor
Journal:  J Clin Invest       Date:  1972-05       Impact factor: 14.808

7.  The presence and biologic activity of cementum-bound endotoxin.

Authors:  J J Aleo; F A De Renzis; P A Farber; A P Varboncoeur
Journal:  J Periodontol       Date:  1974-09       Impact factor: 6.993

8.  Histochemical study of strain L fibroblasts exposed to endotoxin. The effect on cellular organelles.

Authors:  R M Lucas; S Y Chen; J J Aleo
Journal:  J Periodontol       Date:  1979-01       Impact factor: 6.993

  8 in total
  2 in total

1.  Strain-dependent activation of monocytes and inflammatory macrophages by lipopolysaccharide of Porphyromonas gingivalis.

Authors:  L Shapira; C Champagne; T E Van Dyke; S Amar
Journal:  Infect Immun       Date:  1998-06       Impact factor: 3.441

2.  Effect of lipopolysaccharide on proteoglycan synthesis by adult human gingival fibroblasts in vitro.

Authors:  P M Bartold; S J Millar
Journal:  Infect Immun       Date:  1988-08       Impact factor: 3.441

  2 in total

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