Literature DB >> 6246915

Red cell pyrimidine 5'-nucleotidase and glutathione in myeloproliferative and lymphoproliferative disorders.

J E Lieberman, E C Gordon-Smith.   

Abstract

Red cell reduced glutatione (GSH) and pyrimidine 5'-nucleotidase (Pry 5'-NT) were measured in a variety of myeloproliferative and lymphoproliferative disorders. Raised levels of GSH were found in chronic lymphocytic leukaemia, Hodgkin's disease, non-Hodgkin's lymphoma, Waldenstrom's macroglobulinaemia and myeloma. Decreased activity of Pyr 5'-NT was found in acute myeloblastic leukaemia, acute lymphoblastic leukaemia, chronic granulocytic leukaemia, chronic lymphocytic leukaemia, Hodgkin's disease and non-Hodgkin's lymphoma. There was no correlation between the raised GSH levels and decrease Pry 5'-NT levels.

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Year:  1980        PMID: 6246915     DOI: 10.1111/j.1365-2141.1980.tb05912.x

Source DB:  PubMed          Journal:  Br J Haematol        ISSN: 0007-1048            Impact factor:   6.998


  3 in total

1.  Effect of selenium compounds and thiols on human mammary tumor cells.

Authors:  L Yan; J A Yee; L M Boylan; J E Spallholz
Journal:  Biol Trace Elem Res       Date:  1991-08       Impact factor: 3.738

2.  Determination of erythrocyte pyrimidine 5'-nucleotidase activity by 31P nuclear magnetic resonance: comparison of normal controls and multiple sclerosis patients.

Authors:  G L Mendz; C R Middlehurst; P W Kuchel; P A Crossie
Journal:  Experientia       Date:  1986-09-15

3.  Blood glutathione levels in head and neck malignancies.

Authors:  Y P Singh; O P Sachdeva; S K Aggarwal; K Chugh; Harbans Lal
Journal:  Indian J Clin Biochem       Date:  2008-10-01
  3 in total

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