| Literature DB >> 6246909 |
V Mahmoodi, A J Byrne, T E Healy, S Z Hussain.
Abstract
The effect of ketamine on sympathetic ganglion transmission has been studied using the guineapig isolated hypogastric nerve-vas deferens preparation. Ketamine produced a dose-dependent depression in the response to preganglionic stimulation (IC50 2.05 X 10--4 mol litre--1). No change in the response to postganglionic stimulation was recorded. The anti-cholinergic activity of ketamine was confirmed using the frog isolated rectus abdominis.Entities:
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Year: 1980 PMID： 6246909 DOI： 10.1093/bja/52.4.371
Source DB: PubMed Journal: Br J Anaesth ISSN： 0007-0912 Impact factor: 9.166