Literature DB >> 6246025

Inhibitory effect on the formation of chlamydial inclusions in McCoy cells by seminal fluid and some of its components.

P A Mårdh, S Colleen, J Sylwan.   

Abstract

Our purpose was to determine the effect of semen and some of its components upon chlamydial inclusion (CI) count and cytopathogenic effect in cycloheximide-treated McCoy cells. Semen and spermine caused a dose-related decrease in the number of CI, using a standardized infectious dose of Chlamydia trachomatis, immunotype F. Lysozyme in certain concentrations stimulated CI formation, whereas the cations Cu++ and Zn++ produced a cytopathogenic effect and a dose-related reduction of the CI count, EDTA neutralized the effects of the cations and its addition to seminal fluid experimentally infected with C. trachomatis resulted in a greater number of CI than found in control cultures containing only semen.

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Year:  1980        PMID： 6246025

Source DB:  PubMed          Journal:  Invest Urol        ISSN： 0021-0005


  9 in total

1.  Chlamydial antibodies in semen: search for "silent" chlamydial infections in asymptomatic andrological patients.

Authors:  W Weidner; E Floren; O Zimmermann; D Thiele; M Ludwig
Journal:  Infection       Date:  1996 Jul-Aug       Impact factor: 3.553

2.  Effect of seminal plasma on Chlamydia trachomatis strain LB-1 in cell culture.

Authors:  L Hanna; H Keshishyan; G F Brooks; D P Stites; E Jawetz
Journal:  Infect Immun       Date:  1981-04       Impact factor: 3.441

3.  Sexually communicable micro-organisms in human semen samples to be used for artificial insemination by donor.

Authors:  K H Tjiam; B Y van Heijst; A A Polak-Vogelzang; P H Rothbarth; T van Joost; E Stolz; M F Michel
Journal:  Genitourin Med       Date:  1987-04

4.  Nonoxidative antimicrobial effects of human polymorphonuclear leukocyte granule proteins on Chlamydia spp. in vitro.

Authors:  K B Register; C H Davis; P B Wyrick; W M Shafer; J K Spitznagel
Journal:  Infect Immun       Date:  1987-10       Impact factor: 3.441

5.  Chlamydia trachomatis in women attending a gynaecological outpatient clinic with lower genital tract infection.

Authors:  L Svensson; L Weström; P A Mårdh
Journal:  Br J Vener Dis       Date:  1981-08

6.  Antichlamydial activity of lacrimal fluid in patients with trachoma.

Authors:  E A Mahmoud; A E Elhassan; H E Babikir; G Fröman; P A Mårdh
Journal:  Int Ophthalmol       Date:  1994       Impact factor: 2.031

7.  Inhibition of Chlamydia trachomatis growth in McCoy, HeLa, and human prostate cells by zinc.

Authors:  S B Greenberg; D Harris; P Giles; R R Martin; R J Wallace
Journal:  Antimicrob Agents Chemother       Date:  1985-06       Impact factor: 5.191

8.  The binding of Chlamydia trachomatis and zinc to McCoy cells (mouse fibroblasts).

Authors:  B Sugarman; P Agbor
Journal:  Infection       Date:  1987 Jan-Feb       Impact factor: 3.553

9.  Prevalence of Chlamydia trachomatis and Mycoplasma genitalium in pregnant women of Sabzevar-Iran.

Authors:  M Haghighi Hasanabad; M Mohammadzadeh; A Bahador; N Fazel; H Rakhshani; A Majnooni
Journal:  Iran J Microbiol       Date:  2011-09
  9 in total

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