Literature DB >> 6245253

Characterization of RNA synthesized in isolated nuclei of herpes simplex virus type 1-infected KB cells.

M L Miovic, L I Pizer.   

Abstract

Nuclei isolated from herpes simplex virus (HSV)-infected KB cells actively synthesize HSV RNA in vitro; the RNA can be hybridized with HSV DNA or nuclear RNA from HSV-infected cells. Nascent RNA molecules labeled in vivo with 32PO4 were elongated, utilizing the nuclear system to incorporate Hg-CTP at their 3' ends, and then isolated on an affinity column. Hybridization of isolated nascent RNA molecules showed that greater than 50% of them were HSV specific and that more than 25% were self-complementary.

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Year:  1980        PMID: 6245253      PMCID: PMC288576     

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  30 in total

1.  Viral RNA synthesis and levels of DNA-dependent RNA polymerases during replication of adenovirus 2.

Authors:  R Weinmann; J A Jaehning; H J Raskas; R G Roeder
Journal:  J Virol       Date:  1975-01       Impact factor: 5.103

2.  RNA synthesis in cells infected with herpes simplex virus. IX. Evidence for accumulation of abundant symmetric transcripts in nuclei.

Authors:  M Kozak; B Roizman
Journal:  J Virol       Date:  1975-01       Impact factor: 5.103

3.  Symmetrical transcription of herpes simplex virus DNA in infected BSC-1 cells.

Authors:  A Ben Zeev; Y Becker
Journal:  Nature       Date:  1975-04-24       Impact factor: 49.962

4.  RNA synthesis in cells infected with herpes simplex virus. X. Properties of viral symmetric transcripts and of double-stranded RNA prepared from them.

Authors:  B Jacquemont; B Roizman
Journal:  J Virol       Date:  1975-04       Impact factor: 5.103

5.  Transcription of herpes simplex type 1 DNA in nuclei isolated from infected HEp-2 and KB cells.

Authors:  J C Alwine; W L Steinhart; C W Hill
Journal:  Virology       Date:  1974-07       Impact factor: 3.616

6.  Deoxyribonucleic acid synthesis in synchronized mammalian KB cells infected with herpes simplex virus.

Authors:  G H Cohen; R K Vaughan; W C Lawrence
Journal:  J Virol       Date:  1971-06       Impact factor: 5.103

7.  Specific inhibition of nuclear RNA polymerase II by alpha-amanitin.

Authors:  T J Lindell; F Weinberg; P W Morris; R G Roeder; W J Rutter
Journal:  Science       Date:  1970-10-23       Impact factor: 47.728

8.  Transcription of the adenovirus genome by an -amanitine-sensitive ribonucleic acid polymerase in HeLa cells.

Authors:  R Price; S Penman
Journal:  J Virol       Date:  1972-04       Impact factor: 5.103

9.  Role of DNA-dependent RNA polymerases II and III in transcription of the adenovirus genome late in productive infection.

Authors:  R Weinmann; H J Raskas; R G Roeder
Journal:  Proc Natl Acad Sci U S A       Date:  1974-09       Impact factor: 11.205

10.  State of adenovirus 2 deoxyribonucleic acid in the nucleus and its mode of transcription: studies with isolated viral deoxyribonucleic acid-protein complexes and isolated nuclei.

Authors:  R D Wallace; J Kates
Journal:  J Virol       Date:  1972-04       Impact factor: 5.103

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  6 in total

1.  Endogenous endonuclease-induced DNA fragmentation: an early event in cell-mediated cytolysis.

Authors:  R C Duke; R Chervenak; J J Cohen
Journal:  Proc Natl Acad Sci U S A       Date:  1983-10       Impact factor: 11.205

2.  Brain-reactive autoantibody levels in the sera of ageing autoimmune mice.

Authors:  S A Hoffman; D N Arbogast; P M Ford; D W Shucard; R J Harbeck
Journal:  Clin Exp Immunol       Date:  1987-10       Impact factor: 4.330

3.  Polyomavirus DNA is damaged in target cells during cytotoxic T-lymphocyte-mediated killing.

Authors:  K S Sellins; J J Cohen
Journal:  J Virol       Date:  1989-02       Impact factor: 5.103

4.  Functional genomic analysis of herpes simplex virus type 1 counteraction of the host innate response.

Authors:  Tracy Jo Pasieka; Tracey Baas; Victoria S Carter; Sean C Proll; Michael G Katze; David A Leib
Journal:  J Virol       Date:  2006-08       Impact factor: 5.103

5.  Immunogenic DNA-related factors. Nucleosomes spontaneously released from normal murine lymphoid cells stimulate proliferation and immunoglobulin synthesis of normal mouse lymphocytes.

Authors:  D A Bell; B Morrison; P VandenBygaart
Journal:  J Clin Invest       Date:  1990-05       Impact factor: 14.808

6.  Herpes simplex virus-induced changes in cellular and adenovirus RNA metabolism in an adenovirus type 5-transformed human cell line.

Authors:  R M Stenberg; L I Pizer
Journal:  J Virol       Date:  1982-05       Impact factor: 5.103

  6 in total

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