Literature DB >> 6244869

Epstein-Barr virus-positive Burkitt's lymphoma in a German woman during pregnancy.

G W Bornkamm, B Kaduk, G Kachel, U Schneider, K O Fresen, G Schwanitz, P Hermanek.   

Abstract

A fatal case of a Burkitt's lymphoma which occurred in a 34-year-old German woman during pregnancy is described. Nearly all organs showed either diffuse or nodular infiltration by tumor cells. Placenta and fetus were free of detectable tumor tissue. The patient had extremely high antibody titers (1 : 2056), both against Epstein-Barr virus capsid antigen (VCA) and the early antigen complex (EA). Within the tumor cells the Epstein-Barr virus-specific nuclear antigen EBNA and viral DNA was detected. A cell line established from a tumor biopsy displayed a translocation involving chromosomes 2 and 8. The role of Epstein-Barr virus in the development of Burkitt's lymphoma is discussed.

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Year:  1980        PMID： 6244869     DOI： 10.1007/bf01008574

Source DB:  PubMed          Journal:  Blut        ISSN： 0006-5242


  47 in total

1.  Studies on the Epstein-Barr Virus genome and the EBV-determined nuclear antigen in human malignant disease.

Authors:  G Klein
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1975

2.  The Epstein-Barr virus and neoplasia.

Authors:  G Klein
Journal:  N Engl J Med       Date:  1975-12-25       Impact factor: 91.245

3.  Epstein-Barr virus-positive Japanese Burkitt lymphoma.

Authors:  I Miyoshi; S Hiraki; T Tsubota; J Uno; K Nakamura; T Ota; T Hikita; K Hayashi; M Kataoka; T Tanaka; I Kimura; T Sairenji; Y Hinuma
Journal:  Gan       Date:  1978-06

4.  Treatment results of 54 American patients with Burkitt's lymphoma are similar to the African experience.

Authors:  J L Ziegler
Journal:  N Engl J Med       Date:  1977-07-14       Impact factor: 91.245

5.  Characteristic chromosomal abnormalities in biopsies and lymphoid-cell lines from patients with Burkitt and non-Burkitt lymphomas.

Authors:  L Zech; U Haglund; K Nilsson; G Klein
Journal:  Int J Cancer       Date:  1976-01-15       Impact factor: 7.396

6.  Immunofluorescence in cells derived from Burkitt's lymphoma.

Authors:  G Henle; W Henle
Journal:  J Bacteriol       Date:  1966-03       Impact factor: 3.490

7.  Epstein-Barr virus-associated complement-fixing and nuclear antigens in Burkitt lymphoma biopsies.

Authors:  B M Reedman; G Klein; J H Pope; M K Walters; J Hilgers; S Singh; B Johansson
Journal:  Int J Cancer       Date:  1974-06-15       Impact factor: 7.396

8.  Marker band in one chromosome 14 from Burkitt lymphomas.

Authors:  G Manolov; Y Manolova
Journal:  Nature       Date:  1972-05-05       Impact factor: 49.962

Review 9.  Etiology of Burkitt's lymphoma--an alternative hypothesis to a vectored virus.

Authors:  D P Burkitt
Journal:  J Natl Cancer Inst       Date:  1969-01       Impact factor: 13.506

10.  Long-term remissions following one and two-dose chemotherapy for African lymphoma.

Authors:  D Burkitt
Journal:  Cancer       Date:  1967-05       Impact factor: 6.860
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  9 in total

1.  Generation of a variant t(2;8) translocation of Burkitt's lymphoma by site-specific recombination via the kappa light-chain joining signals.

Authors:  P Hartl; M Lipp
Journal:  Mol Cell Biol       Date:  1987-06       Impact factor: 4.272

2.  Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene.

Authors:  H G Klobeck; G W Bornkamm; G Combriato; R Mocikat; H D Pohlenz; H G Zachau
Journal:  Nucleic Acids Res       Date:  1985-09-25       Impact factor: 16.971

3.  Reciprocal recombination products of VK-JK joining reactions in human lymphoid cell lines.

Authors:  S M Deev; G Combriato; H G Klobeck; H G Zachau
Journal:  Nucleic Acids Res       Date:  1987-01-12       Impact factor: 16.971

4.  Three breakpoints of variant t(2;8) translocations in Burkitt's lymphoma cells fall within a region 140 kilobases distal from c-myc.

Authors:  B Henglein; H Synovzik; P Groitl; G W Bornkamm; P Hartl; M Lipp
Journal:  Mol Cell Biol       Date:  1989-05       Impact factor: 4.272

5.  N segment insertion and region-directed somatic hypermutation in a kappa gene of a t(2;8) chromosomal translocation.

Authors:  H G Klobeck; G Combriato; H G Zachau
Journal:  Nucleic Acids Res       Date:  1987-06-25       Impact factor: 16.971

6.  A Burkitt-lymphoma variant translocation (2p-; 8q+) in a patient with ALL, L3 (Burkitt type).

Authors:  J D Rowley; D Variakojis; Y Kaneko; M Cimino
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

7.  Human immunoglobulin kappa light chain genes of subgroups II and III.

Authors:  H G Klobeck; A Meindl; G Combriato; A Solomon; H G Zachau
Journal:  Nucleic Acids Res       Date:  1985-09-25       Impact factor: 16.971

8.  In situ hybridization studies on variant t(2;8) translocations in Burkitt lymphoma lines.

Authors:  H Hameister; S Adolph
Journal:  Hum Genet       Date:  1986-05       Impact factor: 4.132

9.  c-myc and immunoglobulin kappa light chain constant genes are on the 8q+ chromosome of three Burkitt lymphoma lines with t(2;8) translocations.

Authors:  G A Rappold; H Hameister; T Cremer; S Adolph; B Henglein; U K Freese; G M Lenoire; G W Bornkamm
Journal:  EMBO J       Date:  1984-12-01       Impact factor: 11.598
  9 in total

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