Late responses as aids to diagnosis in peripheral neuropathy.

The usefulness of performing late response studies for the detection of peripheral nerve dysfunction has been demonstrated. It has been shown that significant prolongation of the minimal latencies of the H reflex and the F response is present at a time when conventional methods of motor and sensory conduction do not show an abnormality in individual patients. Abnormalities of late responses have been shown to occur in a variety of peripheral neuropathies with "axonal" as well as "segmental demyelination" type of underlying pathology.