Literature DB >> 6244218

Stimulatory effects of gamma-aminohydroxybutyric acid (GABOB) on growth hormone, prolactin and cortisol release in man.

J Takahara, S Yunoki, W Yakushiji, J Yamauchi, H Hosogi, T Ofuji.   

Abstract

Healthy male volunteers injected subcutaneously with 200 mg L-GABOB showed no significant changes in plasma GH, prolactin and cortisol levels. On the other hand, an intrathecal injection of 300 mg D, L-GABOB to cerebrovascular patients caused significant increases in plasma GH, prolactin and cortisol levels at 60 min after injection. These results indicate that GABOB may elicit the secretion of GH, prolactin and ACTH via the central nervous system.

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Year:  1980        PMID: 6244218     DOI: 10.1055/s-2007-996190

Source DB:  PubMed          Journal:  Horm Metab Res        ISSN: 0018-5043            Impact factor:   2.936


  5 in total

Review 1.  Molecular basis of pharmacological therapy in Cushing's disease.

Authors:  Diego Ferone; Claudia Pivonello; Giovanni Vitale; Maria Chiara Zatelli; Annamaria Colao; Rosario Pivonello
Journal:  Endocrine       Date:  2013-11-23       Impact factor: 3.633

Review 2.  Neuroendocrine regulation of human growth hormone secretion. Diagnostic and clinical applications.

Authors:  G Delitala; P Tomasi; R Virdis
Journal:  J Endocrinol Invest       Date:  1988-06       Impact factor: 4.256

3.  Intravenous alprazolam challenge in normal subjects. Biochemical, cardiovascular, and behavioral effects.

Authors:  E D Risby; J K Hsiao; R N Golden; W Z Potter
Journal:  Psychopharmacology (Berl)       Date:  1989       Impact factor: 4.530

4.  Dose-related effects of gamma-amino beta-hydroxy butyric acid (GABOB) infusion on growth hormone secretion in normal women.

Authors:  G B Melis; A M Paoletti; V Mais; N M Mastrapasqua; F Strigini; F Fruzzetti; G Guarnieri; M Gambacciani; P Fioretti
Journal:  J Endocrinol Invest       Date:  1982 Mar-Apr       Impact factor: 4.256

Review 5.  Prolactin-lowering and -releasing drugs. Mechanisms of action and therapeutic applications.

Authors:  E E Müller; V Locatelli; S Cella; A Peñalva; A Novelli; D Cocchi
Journal:  Drugs       Date:  1983-04       Impact factor: 9.546

  5 in total

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