Topographic distribution pattern of Lafora-like bodies in the spinal cord of some animals.

The topographic distribution pattern and morphological features of Lafora-like bodies in the spinal cord of the dog, cat, fox, and baboon were examined by light and electron microscopy. The caudal lumbar and the coccygeal parts of the spinal cords were the predilection sites for the bodies in all animals and were very prominent in the ventral columns and intermediate substance. The bodies mainly composed of branching filaments were preferentially located in neuronal processes and rarely in astocytes. The histochemical characteristics of the bodies were identical in all animals and consisted mainly of polyglucosan.