| Literature DB >> 624361 |
M Garcia-Gracia, J Gervas-Camacho, F V DeFeudis.
Abstract
I.p. injections of desipramine-HCl (100 mg/kg) produced decreases in the contents of several amino acids of mouse brain after 1 h. Using a 10-100 mg/kg range of doses, these effects appeared to be dose-dependent for alpha-alanine and aspartate. These changes may be due, in part, to a decrease in cerebral oxidative metabolism (Krebs cycle activity) which occurs secondarily to desipramine-induced hypothermia.Entities:
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Year: 1978 PMID： 624361 DOI： 10.1007/bf01944694
Source DB: PubMed Journal: Experientia ISSN： 0014-4754