Literature DB >> 6243600

Streptococcal extracellular NAD+ nucleosidase. Characterization of changes occurring during purification.

F J Zahradník.   

Abstract

Purification of streptococcal extracellular NAD+ nucleosidase is associated with changes of kinetic properties. A high-molecular weight component is required for a full activity of the enzyme. The component is not produced by bacteria and is present in the Todd-Hewitt cultivation medium, the beef-heart extract serving primarily as its source. In its effect on the enzyme this component can be replaced with bovine albumin. It follows from the time relationship of the NAD decomposition that the mechanism of the studied enzymic reaction is not hydrolytic. In addition to nicotinamide, a product of polymeric character is formed.

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Year:  1980        PMID： 6243600     DOI： 10.1007/bf02876396

Source DB:  PubMed          Journal:  Folia Microbiol (Praha)        ISSN： 0015-5632            Impact factor:   2.099


  22 in total

1.  Stimulant effect of a heart infusion on streptococcal nicotinamide adenine dinucleotidase (EC 3.2.2.5). (Preliminary report).

Authors:  F Zahradník; L Masková; Z Pravda
Journal:  J Hyg Epidemiol Microbiol Immunol       Date:  1970

2.  Regulatory mechanisms involving nicotinamide adenine nucleotides as allosteric effectors. 3. Control of glucose 6-phosphate dehydrogenase.

Authors:  B D Sanwal
Journal:  J Biol Chem       Date:  1970-04-10       Impact factor: 5.157

3.  Regulatory mechanisms involving nicotinamide adenine nucleotides as all teric effectors. II. Control of phosphoenolpyruvate carboxykinase.

Authors:  J A Wright; B D Sanwal
Journal:  J Biol Chem       Date:  1969-04-10       Impact factor: 5.157

4.  Regulatory mechanisms involving nicotinamide adenine nucleotides as allosteric effectors. I. Control characteristics of malate dehydrogenase.

Authors:  B D Sanwal
Journal:  J Biol Chem       Date:  1969-04-10       Impact factor: 5.157

5.  [The regulation of myocardial metabolism].

Authors:  S E Severin
Journal:  Vestn Akad Med Nauk SSSR       Date:  1966

6.  Studies on the polymer of adenosine diphosphate ribose. II. Characterization of the polymer.

Authors:  R H Reeder; K Ueda; T Honjo; Y Nishizuka; O Hayaishi
Journal:  J Biol Chem       Date:  1967-07-10       Impact factor: 5.157

7.  Studies on the polymer of adenosine diphosphate ribose. I. Enzymic formation from nicotinamide adenine dinuclotide in mammalian nuclei.

Authors:  Y Nishizuka; K Ueda; K Nakazawa; O Hayaishi
Journal:  J Biol Chem       Date:  1967-07-10       Impact factor: 5.157

8.  An enzyme system for de novo biosynthesis of glycogen in Aerobacter aerogenes.

Authors:  L C Gahan; H E Conrad
Journal:  Biochemistry       Date:  1968-11       Impact factor: 3.162

9.  Interaction of spinach leaf adenosine diphosphate glucose alpha-1,4-glucan alpha-4-glucosyl transferase and alpha-1,4-glucan, alpha-1,4-glucan-6-glycosyl transferase in synthesis of branched alpha-glucan.

Authors:  J S Hawker; J L Ozbun; H Ozaki; E Greenberg; J Preiss
Journal:  Arch Biochem Biophys       Date:  1974-02       Impact factor: 4.013

10.  Selective inhibition by preparations of streptococcal filtrates of the oxidative metabolism of mitochondria procured from rabbit myocardium.

Authors:  A W BERNHEIMER; A S CARLSON; A KELLNER
Journal:  J Exp Med       Date:  1956-10-01       Impact factor: 14.307
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  2 in total

1.  Quantitative analysis of streptococcal exoprotein flow to the host receptor--exact basis for therapy of tumors and Alzheimer's disease.

Authors:  F J Zahradník
Journal:  Folia Microbiol (Praha)       Date:  2005       Impact factor: 2.629

2.  Kinetic properties of fractions of extracellular NAD+ nucleosidase from Streptococcus pyogenes as an example of host selection by a pathogen: possible role of serum albumin in the organism.

Authors:  F J Zahradník
Journal:  Folia Microbiol (Praha)       Date:  2001       Impact factor: 2.629
  2 in total

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