Literature DB >> 6243533

Ontogenetic determinants of behavioral responses to morphine in rats.

R J Katz.   

Abstract

Male Sprague-Dawley rats ranging in age from 20 to 110 days were injected with two doses of morphine sulphate, and examined for behavioral activation and catalepsy. Behavioral activation increased with age, while sensitivity to catalepsy declined. Ontogenetic and pharmacological responses suggest possible separate mediation of activation and catalepsy.

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Year:  1980        PMID: 6243533     DOI: 10.1016/0376-8716(80)90189-1

Source DB:  PubMed          Journal:  Drug Alcohol Depend        ISSN: 0376-8716            Impact factor:   4.492


  1 in total

1.  Behavioural effects of selective mu-, kappa-, and delta-opioid agonists in neonatal rats.

Authors:  H C Jackson; I Kitchen
Journal:  Psychopharmacology (Berl)       Date:  1989       Impact factor: 4.530

  1 in total

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