Literature DB >> 624349

The alcohol syndromes: the intrarecombigenic effect of acetaldehyde.

P V Véghelyi, M Osztovics.   

Abstract

Sister chromatid exchange was studied in lymphocyte and fibroblast cultures. Alcohol caused no disturbance under normal conditions but an acetaldehyde level above 40 muM inhibited cell multiplication and elevated SCE considerably. A high acetaldehyde level is thought to elicit the fetal alcohol syndrome, a view supported by clinical and experimental observations.

Entities:  

Mesh：

Substances：

Year:  1978        PMID： 624349     DOI： 10.1007/bf01944673

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  9 in total

1.  [Effects of alcoholized beverages on reproduction in rats].

Authors:  P ASCHKENASY-LELU
Journal:  C R Hebd Seances Acad Sci       Date:  1958-02-24

2.  High blood acetaldehyde levels after ethanol administration. Difference between alcoholic and nonalcoholic subjects.

Authors:  M A Korsten; S Matsuzaki; L Feinman; C S Lieber
Journal:  N Engl J Med       Date:  1975-02-20       Impact factor: 91.245

3.  Liver aldehyde and alcohol dehydrogenase activities in rat strains genetically selected for their ethanol preference.

Authors:  T Koivula; M Koivusalo; K O Lindros
Journal:  Biochem Pharmacol       Date:  1975-10-01       Impact factor: 5.858

Review 4.  The disulfiram--ethanol reaction: a review.

Authors:  T M Kitson
Journal:  J Stud Alcohol       Date:  1977-01

5.  New Giemsa method for the differential staining of sister chromatids.

Authors:  P Perry; S Wolff
Journal:  Nature       Date:  1974-09-13       Impact factor: 49.962

6.  Metabolism of ethanol and acetaldehyde in intact rats during pregnancy.

Authors:  Y A Kesäniemi
Journal:  Biochem Pharmacol       Date:  1974-04-01       Impact factor: 5.858

7.  Enzyme activities and ethanol preference in mice.

Authors:  J R Sheppard; P Albersheim; G E McClearn
Journal:  Biochem Genet       Date:  1968-11       Impact factor: 1.890

8.  Effect of ethanol on the growth and on the liver and brain mitochondrial functions of the offspring of rats.

Authors:  L Pilström; K H Kiessling
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1967

9.  [On the embryo-fetal alcohol syndrome (author's transl)].

Authors:  J R Bierich; F Majewski; R Michaelis; I Tillner
Journal:  Eur J Pediatr       Date:  1976-02-04       Impact factor: 3.183
  9 in total
  2 in total

1.  Sister chromatid exchanges in lymphocytes of normal and alcoholic subjects.

Authors:  J R Lazutka; V Dedonyte; R K Lekevicius
Journal:  Experientia       Date:  1992-05-15

2.  Maternal alcohol consumption and birth weight.

Authors:  P V Véghelyi; M Osztovics; E Szaszovsky
Journal:  Br Med J       Date:  1978-11-11
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.