| Literature DB >> 6243331 |
Abstract
It has been demonstrated that T cells from humans can suppress the transformation of EBV-infected B cells in vitro. In this paper, studies are presented on the mechanism of the suppression. The T cells do not act against the virus itself nor the infection process. They appear to suppress the outgrowth of B cells after they are infected but before they are transformed. The T cells are much less effective in suppressing the outgrowth of the B cells once the latter have transformed (24th post-infection). The significance of these observations to EBV infection and other forms of T cell-mediated anti-EBV immunity is discussed.Entities:
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Year: 1980 PMID： 6243331
Source DB: PubMed Journal: J Immunol ISSN： 0022-1767 Impact factor: 5.422