Literature DB >> 6241614

HLA specificities, lymphocyte subsets, and mitogenic response in Henoch-Schönlein purpura nephritis.

D P Sengar, C D Acharya, N M Wolfish.   

Abstract

The present study failed to show a significant association of Henoch-Schönlein Purpura Nephritis (HSPN) with any of the HLA specificities tested. No abnormalities pertaining to in vitro lymphocyte blastogenesis to various nonspecific mitogens (PHA, PWM, ConA) were detected during the clinical remission of HSPN. During the active phase, HSPN patients developed significant lymphocytosis. The absolute numbers of OKT4+ cells (helper cells) were significantly increased but absolute numbers of OKT8+ cells (suppressor cells) were not altered.

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Year:  1984        PMID: 6241614

Source DB:  PubMed          Journal:  Int J Pediatr Nephrol        ISSN: 0391-6510


  3 in total

1.  Increased transforming growth factor-beta (TGF-beta)-secreting T cells and IgA anti-cardiolipin antibody levels during acute stage of childhood Henoch-Schönlein purpura.

Authors:  Y H Yang; M T Huang; S C Lin; Y T Lin; M J Tsai; B L Chiang
Journal:  Clin Exp Immunol       Date:  2000-11       Impact factor: 4.330

Review 2.  The rheumatic poison: a survey of some published investigations of the immunopathogenesis of Henoch-Schönlein purpura.

Authors:  J F Knight
Journal:  Pediatr Nephrol       Date:  1990-09       Impact factor: 3.714

3.  Cutaneous leukocytoclastic vasculitis: the role of lymphocytes and related immune markers.

Authors:  Thilo Gambichler; Magdalena A Kulik; Marina Skrygan; Isabelle Rooms; Stefan Höxtermann
Journal:  Postepy Dermatol Alergol       Date:  2017-08-01       Impact factor: 1.837

  3 in total

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