Literature DB >> 6239620

Inhibition of rat liver phosphofructokinase-2 by phosphoenolpyruvate and ADP.

M Kretschmer, E Hofmann.   

Abstract

Phosphofructokinase-2 from rat liver is inhibited by phosphoenolpyruvate and ADP. Phosphoenolpyruvate reduces the maximum activity in respect to fructose-6-phosphate and ATP but does not give rise to complete inhibition of phosphofructokinase-2. ADP increases the apparent Michaelis constant of the enzyme for ATP and leaves the maximum activity in respect to ATP unchanged. The apparent Michaelis constant for fructose-6-phosphate is not influenced by ADP.

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Year:  1984        PMID： 6239620     DOI： 10.1016/0006-291x(84)91027-1

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  6 in total

Review 1.  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis.

Authors:  Mark H Rider; Luc Bertrand; Didier Vertommen; Paul A Michels; Guy G Rousseau; Louis Hue
Journal:  Biochem J       Date:  2004-08-01       Impact factor: 3.857

2.  Site-directed mutagenesis of Lys-174, Asp-179 and Asp-191 in the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.

Authors:  L Bertrand; J Deprez; D Vertommen; A Di Pietro; L Hue; M H Rider
Journal:  Biochem J       Date:  1997-02-01       Impact factor: 3.857

3.  Mutagenesis of charged residues in a conserved sequence in the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.

Authors:  L Bertrand; D Vertommen; E Feytmans; A Di Pietro; M H Rider; L Hue
Journal:  Biochem J       Date:  1997-02-01       Impact factor: 3.857

Review 4.  Role of fructose 2,6-bisphosphate in the control of glycolysis in mammalian tissues.

Authors:  L Hue; M H Rider
Journal:  Biochem J       Date:  1987-07-15       Impact factor: 3.857

5.  Site-directed mutagenesis of rat muscle 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: role of Asp-130 in the 2-kinase domain.

Authors:  M H Rider; K M Crepin; M De Cloedt; L Bertrand; L Hue
Journal:  Biochem J       Date:  1994-05-15       Impact factor: 3.857

6.  Bistability in glycolysis pathway as a physiological switch in energy metabolism.

Authors:  Bhanu Chandra Mulukutla; Andrew Yongky; Prodromos Daoutidis; Wei-Shou Hu
Journal:  PLoS One       Date:  2014-06-09       Impact factor: 3.240
  6 in total

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