Literature DB >> 6237695

Characterization of a laminin receptor from human breast carcinoma tissue.

S H Barsky, C N Rao, D Hyams, L A Liotta.   

Abstract

Human breast carcinoma contains high-affinity receptors for the basement membrane glycoprotein laminin. Plasma membranes isolated from tissue samples of human breast carcinoma exhibit specific, saturable, reversible, and displaceable binding to laminin. Fibronectin, collagen, and serum proteins fail to displace this bound laminin. Scatchard analysis is linear with a Kd of 1.8 X 10(-9) M. The laminin receptor, isolated and purified 1200-fold by laminin-affinity chromatography, exhibits a molecular weight of 67 000 daltons as determined by gel electrophoresis. The receptor was verified to be located on the cell surface of the invading breast carcinoma cells by immunohistologic studies utilizing a peroxidase-conjugated fragment of the laminin molecule which contained the receptor-binding domain.

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Year:  1984        PMID： 6237695     DOI： 10.1007/bf01806483

Source DB:  PubMed          Journal:  Breast Cancer Res Treat        ISSN： 0167-6806            Impact factor:   4.872


  17 in total

1.  Laminin--a glycoprotein from basement membranes.

Authors:  R Timpl; H Rohde; P G Robey; S I Rennard; J M Foidart; G R Martin
Journal:  J Biol Chem       Date:  1979-10-10       Impact factor: 5.157

2.  Monoclonal antibodies to the human laminin receptor recognize structurally distinct sites.

Authors:  L A Liotta; P Horan Hand; C N Rao; G Bryant; S H Barsky; J Schlom
Journal:  Exp Cell Res       Date:  1985-01       Impact factor: 3.905

3.  Loss of basement membrane components by invasive tumors but not by their benign counterparts.

Authors:  S H Barsky; G P Siegal; F Jannotta; L A Liotta
Journal:  Lab Invest       Date:  1983-08       Impact factor: 5.662

4.  Characterization of the mammalian beta-2 receptor in 8 M urea.

Authors:  C J Homcy; D Sylvestre
Journal:  Biochem Biophys Res Commun       Date:  1982-09-30       Impact factor: 3.575

5.  Isolation of a tumor cell laminin receptor.

Authors:  N C Rao; S H Barsky; V P Terranova; L A Liotta
Journal:  Biochem Biophys Res Commun       Date:  1983-03-29       Impact factor: 3.575

6.  Isolation of a subunit of laminin and its role in molecular structure and tumor cell attachment.

Authors:  C N Rao; I M Margulies; T S Tralka; V P Terranova; J A Madri; L A Liotta
Journal:  J Biol Chem       Date:  1982-08-25       Impact factor: 5.157

7.  Role of laminin in the attachment and metastasis of murine tumor cells.

Authors:  V P Terranova; L A Liotta; R G Russo; G R Martin
Journal:  Cancer Res       Date:  1982-06       Impact factor: 12.701

8.  Laminin receptor on human breast carcinoma cells.

Authors:  V P Terranova; C N Rao; T Kalebic; I M Margulies; L A Liotta
Journal:  Proc Natl Acad Sci U S A       Date:  1983-01       Impact factor: 11.205

9.  Isolation of a laminin-binding protein from muscle cell membranes.

Authors:  H Lesot; U Kühl; K Mark
Journal:  EMBO J       Date:  1983       Impact factor: 11.598

10.  Isolation of a cell surface receptor protein for laminin from murine fibrosarcoma cells.

Authors:  H L Malinoff; M S Wicha
Journal:  J Cell Biol       Date:  1983-05       Impact factor: 10.539
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  12 in total

1.  Laminin-mediated adhesion in metastatic rat rhabdomyosarcoma cell lines involves prominent interactions with the laminin E8 fragment.

Authors:  J C Lissitzky; M Bouzon; E Loret; M F Poupon; P M Martin
Journal:  Clin Exp Metastasis       Date:  1989 Jul-Aug       Impact factor: 5.150

2.  Normal epithelial antigens recognized by GB3 and GB5 are diminished in intraductal and lost in infiltrating human breast carcinomas.

Authors:  C J Yeh; B L Hsi; F Ettore
Journal:  Breast Cancer Res Treat       Date:  1986       Impact factor: 4.872

3.  Laminin receptors on Candida albicans germ tubes.

Authors:  J P Bouchara; G Tronchin; V Annaix; R Robert; J M Senet
Journal:  Infect Immun       Date:  1990-01       Impact factor: 3.441

4.  Control pathways of the 67 kDa laminin binding protein: surface expression and activity of a new ligand binding domain.

Authors:  T H Landowski; S Uthayakumar; J R Starkey
Journal:  Clin Exp Metastasis       Date:  1995-09       Impact factor: 5.150

5.  Gene expression profiling identifies genes predictive of oral squamous cell carcinoma.

Authors:  Chu Chen; Eduardo Méndez; John Houck; Wenhong Fan; Pawadee Lohavanichbutr; Dave Doody; Bevan Yueh; Neal D Futran; Melissa Upton; D Gregory Farwell; Stephen M Schwartz; Lue Ping Zhao
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2008-07-31       Impact factor: 4.254

6.  1 alpha,25-Dihydroxyvitamin D3 inhibits the invasive potential of human breast cancer cells in vitro.

Authors:  C M Hansen; T L Frandsen; N Brünner; L Binderup
Journal:  Clin Exp Metastasis       Date:  1994-05       Impact factor: 5.150

7.  Genetic identification of antigens exposed in damaged endothelial cells as laminin-binding proteins.

Authors:  D C Ireland; E L Spring; E Moiseeva; D P de Bono
Journal:  Clin Exp Immunol       Date:  1998-05       Impact factor: 4.330

8.  Binding of Paracoccidioides brasiliensis to laminin through surface glycoprotein gp43 leads to enhancement of fungal pathogenesis.

Authors:  A P Vicentini; J L Gesztesi; M F Franco; W de Souza; J Z de Moraes; L R Travassos; J D Lopes
Journal:  Infect Immun       Date:  1994-04       Impact factor: 3.441

9.  Two distinct cell-binding domains in laminin can independently promote nonneuronal cell adhesion and spreading.

Authors:  S L Goodman; R Deutzmann; K von der Mark
Journal:  J Cell Biol       Date:  1987-07       Impact factor: 10.539

10.  Isolation and characterization of a laminin-binding protein from rat and chick muscle.

Authors:  D E Hall; K A Frazer; B C Hann; L F Reichardt
Journal:  J Cell Biol       Date:  1988-08       Impact factor: 10.539
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