Literature DB >> 6235758

The role of fibrinolysis in the therapy of peripheral vascular disease.

C M Ambrus, J L Ambrus, H Gastpar, S D Sharma, O W Suh, R H Moore, P Williams.   

Abstract

In vivo thrombolytic studies in stumptailed monkeys indicated that pentoxifylline potentiates thrombolysis induced by urokinase activated human plasmin. Pentoxifylline as well as prostaglandin E1 released plasminogen activators and activated the fibrinolysin system. From this point of view pentoxifylline and prostaglandin E1 synergized with each other. Pentoxifylline potentiated the thrombolytic effect of prostaglandin E1 in vivo.

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Year:  1984        PMID: 6235758     DOI: 10.1177/000331978403500706

Source DB:  PubMed          Journal:  Angiology        ISSN: 0003-3197            Impact factor:   3.619


  1 in total

Review 1.  Pentoxifylline. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic efficacy.

Authors:  A Ward; S P Clissold
Journal:  Drugs       Date:  1987-07       Impact factor: 9.546

  1 in total

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